SCOPe 2.07: Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain

Lineage for Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (15 families)

5. Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain [82253] (4 proteins)
   Glycosyl hydrolase family 67, GH67; structurally related to GH20; contains extra C-terminal alpha-helical subdomain

Proteins:

1. alpha-D-glucuronidase catalytic domain [82254] (2 species)
   inverting reaction mechanism

   1. Species Bacillus stearothermophilus [TaxId:1422] [82256] (7 PDB entries)

   2. Species Pseudomonas cellulosa [TaxId:155077] [82255] (5 PDB entries)

2. Glucosaminidase GH84, catalytic domain [141790] (1 species)

   • Species Bacteroides thetaiotaomicron [TaxId:818] [141791] (8 PDB entries)
     Uniprot Q89ZI2 148-457

3. Hyaluronidase catalytic domain [141792] (1 species)

   • Species Clostridium perfringens [TaxId:1502] [141793] (8 PDB entries)
     Uniprot Q8XL08 179-495

4. automated matches [254553] (3 species)
   not a true protein

   1. Species Bacteroides thetaiotaomicron [TaxId:226186] [255268] (4 PDB entries)

   2. Species Clostridium perfringens [TaxId:1502] [255690] (2 PDB entries)

   3. Species Escherichia coli [TaxId:83333] [399127] (1 PDB entry)

More info for Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain

Timeline for Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain:

• Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain first appeared in SCOP 1.63, called Family c.1.8.10: alpha-D-glucuronidase catalytic domain
  
• Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain appears in SCOPe 2.06
  
• Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain appears in the current release, SCOPe 2.08