SCOPe 2.04: Superfamily f.21.2: Fumarate reductase respiratory complex transmembrane subunits

Lineage for Superfamily f.21.2: Fumarate reductase respiratory complex transmembrane subunits

1. Root: SCOPe 2.04

2. Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)

3. Fold f.21: Heme-binding four-helical bundle [81344] (3 superfamilies)
   core: four transmembrane helices, up-and-down bundle, binds one or two heme groups in between the helices

4. Superfamily f.21.2: Fumarate reductase respiratory complex transmembrane subunits [81343] (2 families)
   two distinct families: in one family the common fold is contained in a single-chain subunit, in the other it is formed by two chains

Families:

1. f.21.2.1: Fumarate reductase respiratory complex cytochrome b subunit, FrdC [56910] (2 proteins)
   duplication: consists of two structural repeats; the heme-binding sites are related by pseudo two fold symmetry

2. f.21.2.2: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) [81373] (7 proteins)
   consists of two homologous non-identical subunits that form a heterodimer; may or may not contain heme groups

More info for Superfamily f.21.2: Fumarate reductase respiratory complex transmembrane subunits

Timeline for Superfamily f.21.2: Fumarate reductase respiratory complex transmembrane subunits:

• Superfamily f.21.2: Fumarate reductase respiratory complex transmembrane subunits first appeared in SCOP 1.63
  
• Superfamily f.21.2: Fumarate reductase respiratory complex transmembrane subunits appears in SCOPe 2.03
  
• Superfamily f.21.2: Fumarate reductase respiratory complex transmembrane subunits appears in SCOPe 2.05
  
• Superfamily f.21.2: Fumarate reductase respiratory complex transmembrane subunits appears in the current release, SCOPe 2.08