SCOPe 2.05: Family b.2.5.6: RUNT domain

Lineage for Family b.2.5.6: RUNT domain

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (8 families)

5. Family b.2.5.6: RUNT domain [81318] (2 proteins)
   automatically mapped to Pfam PF00853

Proteins:

1. Acute myeloid leukemia 1 protein (AML1), RUNT domain [49439] (2 species)
   synonym: core binding factor alpha, cbfa

   1. Species Human (Homo sapiens) [TaxId:9606] [49440] (5 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [63684] (14 PDB entries)
      almost identical sequence to the human protein

2. automated matches [190872] (1 species)
   not a true protein

   • Species Mouse (Mus musculus) [TaxId:10090] [188223] (1 PDB entry)

More info for Family b.2.5.6: RUNT domain

Timeline for Family b.2.5.6: RUNT domain:

• Family b.2.5.6: RUNT domain first appeared in SCOP 1.63
  
• Family b.2.5.6: RUNT domain appears in SCOPe 2.04
  
• Family b.2.5.6: RUNT domain appears in SCOPe 2.06
  
• Family b.2.5.6: RUNT domain appears in the current release, SCOPe 2.08