Lineage for Family c.37.1.20: Extended AAA-ATPase domain

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families) (S)
    division into families based on beta-sheet topologies
  5. Family c.37.1.20: Extended AAA-ATPase domain [81269] (43 proteins)
    fold is similar to that of RecA, but lacks the last two strands, followed by a family-specific Arg-finger domain

Proteins:

  1. AAA domain of cell division protein FtsH [82418] (3 species)
    ATP-dependent protease
    1. Species Escherichia coli [TaxId:562] [82419] (1 PDB entry)
    2. Species Thermotoga maritima [TaxId:2336] [142325] (3 PDB entries)
      Uniprot Q9WZ49 150-402
    3. Species Thermus thermophilus [TaxId:274] [82420] (4 PDB entries)
  2. Archaeal ATPase SSO1545 [142326] (1 species)
    member of Pfam PF01637 family; overall structural similarity to the archael CDC6-like protein APE0102
  3. ATPase domain of protease Lon (La) [102393] (2 species)
    1. Species Brevibacillus thermoruber [TaxId:33942] [227843] (1 PDB entry)
    2. Species Escherichia coli [TaxId:562] [102394] (1 PDB entry)
  4. ATPase subunit of magnesium chelatase, BchI [64040] (1 species)
  5. CDC6, N-domain [52715] (1 species)
    contains "winged helix" DNA-binding domain after the family specific domains
  6. CDC6-like protein APE0152, N-terminal domain [117556] (1 species)
  7. CED-4, NB-ARC domain [159577] (1 species)
    belongs to Pfam PF00931
  8. Chromosomal replication initiation factor DnaA [82416] (1 species)
    contains TrpR-like DNA-binding domain after the family specific domains
  9. ClpA, an Hsp100 chaperone, AAA+ modules [82421] (1 species)
    duplication: two AAA+ modules; the first module is structurally similar to the CDC6 module whereas the second module to the HslU module
  10. ClpX [102391] (1 species)
    ATPase subunit of ATP-dependent protease
  11. delta prime subunit of DNA polymerase III, N-domain [52711] (1 species)
    contains additional alpha-helical domain after the family specific domains
  12. delta subunit of DNA polymerase III, N-domain [64033] (1 species)
  13. gamma subunit of DNA polymerase III, N-domain [64031] (2 species)
    1. Species Escherichia coli [TaxId:562] [64032] (3 PDB entries)
      Uniprot P06710 5-368
    2. Species Thermotoga maritima [TaxId:2336] [142324] (1 PDB entry)
      Uniprot Q9WZM9 11-208
  14. Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein [52717] (1 species)
  15. Holliday junction helicase RuvB [52713] (2 species)
    contains "winged helix" DNA-binding domain after the family specific domains
    1. Species Thermotoga maritima [TaxId:2336] [64037] (6 PDB entries)
    2. Species Thermus thermophilus [TaxId:274] [52714] (3 PDB entries)
  16. HslU [52721] (2 species)
    ATPase subunit of ATP-dependent protease
    1. Species Escherichia coli [TaxId:562] [52722] (11 PDB entries)
    2. Species Haemophilus influenzae [TaxId:727] [52723] (6 PDB entries)
  17. Membrane fusion ATPase VCP/p97 [64038] (2 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [313486] (5 PDB entries)
    2. Species Mouse (Mus musculus) [TaxId:10090] [64039] (4 PDB entries)
  18. Papillomavirus large T antigen helicase domain [89688] (1 species)
  19. Proteasome regulatory particle base subunit Rpt1, C-terminal domain [346072] (1 species)
  20. Proteasome regulatory particle base subunit Rpt1, OB-fold domain [346073] (1 species)
  21. Proteasome regulatory particle base subunit Rpt2, C-terminal domain [346074] (1 species)
  22. Proteasome regulatory particle base subunit Rpt2, OB-fold domain [346075] (1 species)
  23. Proteasome regulatory particle base subunit Rpt3, C-terminal domain [346076] (1 species)
  24. Proteasome regulatory particle base subunit Rpt3, OB-fold domain [346077] (1 species)
  25. Proteasome regulatory particle base subunit Rpt4, C-terminal domain [346078] (1 species)
  26. Proteasome regulatory particle base subunit Rpt4, OB-fold domain [346079] (1 species)
  27. Proteasome regulatory particle base subunit Rpt5, C-terminal domain [346080] (1 species)
  28. Proteasome regulatory particle base subunit Rpt5, OB-fold domain [346081] (1 species)
  29. Proteasome regulatory particle base subunit Rpt6, C-terminal domain [346082] (1 species)
  30. Proteasome regulatory particle base subunit Rpt6, OB-fold domain [346083] (1 species)
  31. Proteasome-activating nucleotidase PAN, C-terminal domain [346084] (1 species)
  32. Rep 40 protein helicase domain [110564] (1 species)
  33. Replication factor C [64035] (1 species)
    contains additional alpha-helical domain after the family specific domains
  34. Replication factor C1 [110566] (1 species)
  35. Replication factor C2 [110572] (1 species)
  36. Replication factor C3 [110570] (1 species)
  37. Replication factor C4 [110568] (1 species)
  38. Replication factor C5 [110574] (1 species)
  39. Replication protein E1 helicase domain [110576] (1 species)
  40. Transcriptional activator sigm54 (NtrC1), C-terminal domain [102389] (1 species)
  41. automated matches [190766] (8 species)
    not a true protein
    1. Species Aquifex aeolicus [TaxId:63363] [226012] (1 PDB entry)
    2. Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [373406] (1 PDB entry)
    3. Species Escherichia coli [TaxId:562] [382113] (1 PDB entry)
    4. Species Escherichia coli [TaxId:83333] [384333] (3 PDB entries)
    5. Species Human (Homo sapiens) [TaxId:9606] [255867] (6 PDB entries)
    6. Species Jc polyomavirus [TaxId:10632] [319763] (4 PDB entries)
    7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [187983] (1 PDB entry)
    8. Species Neisseria meningitidis [TaxId:487] [420066] (1 PDB entry)
  42. ClpB, AAA+ modules, N-terminal domain [418980] (2 species)
    ATPase subunit of ATP-dependent protease; similar domain organization to ClpA
    1. Species Escherichia coli [TaxId:562] [75212] (1 PDB entry)
    2. Species Thermus thermophilus [TaxId:274] [419448] (1 PDB entry)
  43. ClpB, AAA+ modules, C-terminal domain [418981] (1 species)
    ATPase subunit of ATP-dependent protease; similar domain organization to ClpA

More info for Family c.37.1.20: Extended AAA-ATPase domain

Timeline for Family c.37.1.20: Extended AAA-ATPase domain: