Lineage for Family c.37.1.19: Tandem AAA-ATPase domain

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 313180Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 313181Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (21 families) (S)
    division into families based on beta-sheet topologies
  5. 314510Family c.37.1.19: Tandem AAA-ATPase domain [81268] (6 proteins)
    duplication: tandem repeat of two RecA-like (AAA) domains

Proteins:

  1. 314511DEXX box DNA helicase [52701] (2 species)
    each AAA domain contains an all-alpha insert subdomain
    1. 314512Species Bacillus stearothermophilus, PcrA [TaxId:1422] [52702] (5 PDB entries)
    2. 314524Species Escherichia coli, RepD [TaxId:562] [52703] (1 PDB entry)
  2. 314529Initiation factor 4a [52706] (1 species)
    homologous to UvrB
  3. 314537Nucleotide excision repair enzyme UvrB [52708] (2 species)
    contains large insertions in the first AAA domain
    1. 314538Species Bacillus caldotenax [TaxId:1395] [52710] (2 PDB entries)
    2. 314543Species Thermus thermophilus [TaxId:274] [52709] (2 PDB entries)
  4. 314548Putative DEAD box RNA helicase [52704] (1 species)
    homologous to eIF4a and UrvB
  5. 314554RecG helicase domain [69494] (1 species)
  6. 314558Translocation ATPase SecA, nucleotide-binding domains [82414] (2 species)
    a pre-protein crosslinking domain inserted in the first AAA domain
    1. 314559Species Bacillus subtilis [TaxId:1423] [82415] (2 PDB entries)
    2. 314564Species Mycobacterium tuberculosis [TaxId:1773] [89687] (2 PDB entries)

More info for Family c.37.1.19: Tandem AAA-ATPase domain

Timeline for Family c.37.1.19: Tandem AAA-ATPase domain: