SCOPe 2.03: Domain d1ngya2: 1ngy A:108-213

Lineage for d1ngya2 (1ngy A:108-213)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (147 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)
   SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody

8. Domain d1ngya2: 1ngy A:108-213 [80497]
   Other proteins in same PDB: d1ngya1, d1ngyb1, d1ngyb2
   part of metal chelatase catalytic Fab 7G12; chimeric mature antibody

Details for d1ngya2

PDB Entry: 1ngy, 2.2 Å

PDB Description: Chimeric Mature Fab 7g12-Apo

PDB Compounds: (A:) Mature Metal Chelatase Catalytic Antibody, Light chain

SCOPe Domain Sequences for d1ngya2:

Sequence; same for both SEQRES and ATOM records:

>d1ngya2 b.1.1.2 (A:108-213) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrge

Timeline for d1ngya2:

• d1ngya2 first appeared in SCOP 1.63
  
• d1ngya2 appears in SCOPe 2.02
  
• d1ngya2 appears in SCOPe 2.04
  
• d1ngya2 appears in the current release, SCOPe 2.08