Lineage for d1n8zc3 (1n8z C:166-322)

  1. Root: SCOPe 2.05
  2. 1959977Class g: Small proteins [56992] (92 folds)
  3. 1960255Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
    disulfide-bound fold; contains beta-hairpin with two adjacent disulfides
  4. 1961098Superfamily g.3.9: Growth factor receptor domain [57184] (2 families) (S)
  5. 1961099Family g.3.9.1: Growth factor receptor domain [57185] (9 proteins)
  6. 1961130Protein Protooncoprotein Her2 extracellular domain [82889] (2 species)
  7. 1961131Species Human (Homo sapiens) [TaxId:9606] [82890] (2 PDB entries)
  8. 1961132Domain d1n8zc3: 1n8z C:166-322 [80324]
    Other proteins in same PDB: d1n8za1, d1n8za2, d1n8zb1, d1n8zb2, d1n8zc1, d1n8zc2
    complexed with nag, so4

Details for d1n8zc3

PDB Entry: 1n8z (more details), 2.52 Å

PDB Description: crystal structure of extracellular domain of human her2 complexed with herceptin fab
PDB Compounds: (C:) Receptor protein-tyrosine kinase erbB-2

SCOPe Domain Sequences for d1n8zc3:

Sequence, based on SEQRES records: (download)

>d1n8zc3 g.3.9.1 (C:166-322) Protooncoprotein Her2 extracellular domain {Human (Homo sapiens) [TaxId: 9606]}
rsrachpcspmckgsrcwgessedcqsltrtvcaggcarckgplptdccheqcaagctgp
khsdclaclhfnhsgicelhcpalvtyntdtfesmpnpegrytfgascvtacpynylstd
vgsctlvcplhnqevtaedgtqrcekcskpcarvcyg

Sequence, based on observed residues (ATOM records): (download)

>d1n8zc3 g.3.9.1 (C:166-322) Protooncoprotein Her2 extracellular domain {Human (Homo sapiens) [TaxId: 9606]}
rsrachpcspmckgsrcwgessedcqsltrtvcaggcarckgplptdccheqcaagctgp
khsdclaclhfnhsgicelhcpalvtyntdtfesmpnpegrytfgascvtacpynylstd
vgsctlvcplhnqevtatqrcekcskpcarvcyg

SCOPe Domain Coordinates for d1n8zc3:

Click to download the PDB-style file with coordinates for d1n8zc3.
(The format of our PDB-style files is described here.)

Timeline for d1n8zc3: