SCOPe 2.01: Domain d1n8za2: 1n8z A:108-214

Lineage for d1n8za2 (1n8z A:108-214)

Root: SCOPe 2.01
Class b: All beta proteins [48724] (174 folds)
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (5 families)
Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (5 species)

Species Human (Homo sapiens) [TaxId:9606] [88569] (132 PDB entries)
including humanized antibodies (chimeric proteins with human constant domains)
SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody

Domain d1n8za2: 1n8z A:108-214 [80319]
Other proteins in same PDB: d1n8za1, d1n8zb1, d1n8zb2, d1n8zc1, d1n8zc2, d1n8zc3, d1n8zc4
part of humanized Fab 4D5, herceptin
complexed with nag, so4

Details for d1n8za2

PDB Entry: 1n8z (more details), 2.52 Å

PDB Description: crystal structure of extracellular domain of human her2 complexed with herceptin fab

PDB Compounds: (A:) Herceptin Fab (antibody) - light chain

SCOPe Domain Sequences for d1n8za2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1n8za2 b.1.1.2 (A:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

SCOPe Domain Coordinates for d1n8za2:

Click to download the PDB-style file with coordinates for d1n8za2.
(The format of our PDB-style files is described here.)

Timeline for d1n8za2: