SCOP 1.63: Domain d1n8za1: 1n8z A:1-107

Lineage for d1n8za1 (1n8z A:1-107)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (15 proteins)

6. Protein Immunoglobulin (variable domains of L and H chains) [48749] (228 species)

7. Species Herceptin Fab 4D5 (synthetic, humanised version), kappa L chain [48771] (4 PDB entries)

8. Domain d1n8za1: 1n8z A:1-107 [80318]
   Other proteins in same PDB: d1n8za2, d1n8zb2, d1n8zc1, d1n8zc2, d1n8zc3, d1n8zc4

Details for d1n8za1

PDB Entry: 1n8z, 2.52 Å

PDB Description: crystal structure of extracellular domain of human her2 complexed with herceptin fab

SCOP Domain Sequences for d1n8za1:

Sequence; same for both SEQRES and ATOM records:

>d1n8za1 b.1.1.1 (A:1-107) Immunoglobulin (variable domains of L and H chains) {Herceptin Fab 4D5 (synthetic, humanised version), kappa L chain}
diqmtqspsslsasvgdrvtitcrasqdvntavawyqqkpgkapklliysasflysgvps
rfsgsrsgtdftltisslqpedfatyycqqhyttpptfgqgtkveik

Timeline for d1n8za1:

• d1n8za1 is new in SCOP 1.63
  
• d1n8za1 appears in SCOP 1.65
  
• d1n8za1 appears in the current release, SCOPe 2.08