Lineage for d1n49b_ (1n49 B:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2391025Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2391026Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2391027Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2391043Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. 2391281Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (514 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 2392170Domain d1n49b_: 1n49 B: [79988]
    complexed with rit

Details for d1n49b_

PDB Entry: 1n49 (more details), 2.2 Å

PDB Description: viability of a drug-resistant hiv-1 protease variant: structural insights for better anti-viral therapy
PDB Compounds: (B:) Protease

SCOPe Domain Sequences for d1n49b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1n49b_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}

SCOPe Domain Coordinates for d1n49b_:

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Timeline for d1n49b_: