SCOP 1.65: Domain d1n0hb2: 1n0h B:83-270

Lineage for d1n0hb2 (1n0h B:83-270)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465

4. Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families)
   there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
   two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules

5. Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (5 proteins)
   the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology

6. Protein Acetohydroxyacid synthase catalytic subunit [88733] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88734] (2 PDB entries)

8. Domain d1n0hb2: 1n0h B:83-270 [79738]
   Other proteins in same PDB: d1n0ha1, d1n0ha3, d1n0hb1, d1n0hb3
   complexed with ayd, cie, dtt, fad, k, mg, tpp

Details for d1n0hb2

PDB Entry: 1n0h, 2.8 Å

PDB Description: crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorimuron ethyl

SCOP Domain Sequences for d1n0hb2:

Sequence; same for both SEQRES and ATOM records:

>d1n0hb2 c.36.1.5 (B:83-270) Acetohydroxyacid synthase catalytic subunit {Baker's yeast (Saccharomyces cerevisiae)}
pdmdtsfvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdkfnfvlpkheqga
ghmaegyarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgqvptsaigtdafq
eadvvgisrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlpkdvtaailrnpi
ptkttlps

Timeline for d1n0hb2:

• d1n0hb2 first appeared in SCOP 1.63
  
• d1n0hb2 appears in SCOP 1.67
  
• d1n0hb2 appears in the current release, SCOPe 2.08