Lineage for d1mvca_ (1mvc A:)

  1. Root: SCOP 1.63
  2. 208553Class a: All alpha proteins [46456] (171 folds)
  3. 217440Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 217441Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family) (S)
  5. 217442Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (20 proteins)
  6. 217562Protein Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)
  7. 217563Species Human (Homo sapiens) [TaxId:9606] [48511] (10 PDB entries)
  8. 217569Domain d1mvca_: 1mvc A: [79499]
    complexed with co-activator peptide
    complexed with bm6

Details for d1mvca_

PDB Entry: 1mvc (more details), 1.9 Å

PDB Description: Crystal structure of the human RXR alpha ligand binding domain bound to the synthetic agonist compound BMS 649 and a coactivator peptide

SCOP Domain Sequences for d1mvca_:

Sequence, based on SEQRES records: (download)

>d1mvca_ a.123.1.1 (A:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens)}
dmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakriph
fselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdr
vltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhky
peqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap

Sequence, based on observed residues (ATOM records): (download)

>d1mvca_ a.123.1.1 (A:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens)}
dmpverileaelavepdpvtnicqaadkqlftlvewakriphfselplddqvillragwn
elliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdkte
lgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalr
siglkclehlfffkligdtpidtflmemleap

SCOP Domain Coordinates for d1mvca_:

Click to download the PDB-style file with coordinates for d1mvca_.
(The format of our PDB-style files is described here.)

Timeline for d1mvca_: