SCOPe 2.01: Domain d1mu2a2: 1mu2 A:3-429

Lineage for d1mu2a2 (1mu2 A:3-429)

1. Root: SCOPe 2.01

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (3 species)

7. Species Human immunodeficiency virus type 2 [TaxId:11709] [82840] (1 PDB entry)

8. Domain d1mu2a2: 1mu2 A:3-429 [79470]
   Other proteins in same PDB: d1mu2a1
   complexed with gol, so4

Details for d1mu2a2

PDB Entry: 1mu2, 2.35 Å

PDB Description: crystal structure of hiv-2 reverse transcriptase

PDB Compounds: (A:) hiv-2 rt

SCOPe Domain Sequences for d1mu2a2:

Sequence, based on SEQRES records:

>d1mu2a2 e.8.1.2 (A:3-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 2 [TaxId: 11709]}
akvepikimlkpgkdgpklrqwpltkekiealkeicekmekegqleeapptnpyntptfa
ikkkdknkwrmlidfrelnkvtqdfteiqlgiphpaglakkrritvldvgdayfsiplhe
dfrpytaftlpsvnnaepgkryiykvlpqgwkgspaifqhtmrqvlepfrkankdviiiq
ymddiliasdrtdlehdrvvlqlkellnglgfstpdekfqkdppyhwmgyelwptkwklq
kiqlpqkeiwtvndiqklvgvlnwaaqlypgiktkhlcrlisgkmtlteevqwtelaeae
leenriilsqeqeghyyqeekeleatvqkdqdnqwtykihqeekilkvgkyakvknthtn
girllaqvvqkigkealviwgripkfhlpvereiweqwwdnywqvtwipdwdfvstpplv
rlafnlv

Sequence, based on observed residues (ATOM records):

>d1mu2a2 e.8.1.2 (A:3-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 2 [TaxId: 11709]}
akvepikimlkpgkdgpklrqwpltkekiealkeicekmekegqleeapptnpyntptfa
ikkkdrmlidfrelnkvtqdfteiqlgiphpaglakkrritvldvgdayfsiplhedfrp
ytaftlkryiykvlpqgwkgspaifqhtmrqvlepfrkankdviiiqymddiliasdrtd
lehdrvvlqlkellnglgfstpdekfqkdppyhwmgyelwptkwklqkiqlpqkeiwtvn
diqklvgvlnwaaqlypgiktkhlcrlisgkmtlteevqwtelaeaeleenriilsqeqe
ghyyqeekeleatvqkdqdnqwtykihqeekilkvgkyakvthtngirllaqvvqkigke
alviwgripkfhlpvereiweqwwdnywqvtwipdwdfvstpplvrlafnlv

Timeline for d1mu2a2:

• d1mu2a2 first appeared in SCOP 1.63
  
• d1mu2a2 appears in SCOP 1.75
  
• d1mu2a2 appears in SCOPe 2.02
  
• d1mu2a2 appears in the current release, SCOPe 2.08