SCOPe 2.06: Domain d1mq5a_: 1mq5 A:

Lineage for d1mq5a_ (1mq5 A:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Coagulation factor Xa, protease domain [50574] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50575] (57 PDB entries)
   Uniprot P00742 235-467

8. Domain d1mq5a_: 1mq5 A: [79400]
   Other proteins in same PDB: d1mq5l_
   complexed with ca, gol, xlc

Details for d1mq5a_

PDB Entry: 1mq5, 2.1 Å

PDB Description: crystal structure of 3-chloro-n-[4-chloro-2-[[(4-chlorophenyl) amino]carbonyl]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]-2- thiophenecarboxamide complexed with human factor xa

PDB Compounds: (A:) coagulation factor x heavy chain

SCOPe Domain Sequences for d1mq5a_:

Sequence; same for both SEQRES and ATOM records:

>d1mq5a_ b.47.1.2 (A:) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk

Timeline for d1mq5a_:

• d1mq5a_ first appeared in SCOP 1.63
  
• d1mq5a_ appears in SCOPe 2.05
  
• d1mq5a_ appears in SCOPe 2.07
  
• d1mq5a_ appears in the current release, SCOPe 2.08