SCOPe 2.06: Domain d1mkgd_: 1mkg D:

Lineage for d1mkgd_ (1mkg D:)

1. Root: SCOPe 2.06

2. Class g: Small proteins [56992] (94 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.1: Platelet-derived growth factor-like [57502] (4 proteins)

6. Protein Vascular endothelial growth factor, VEGF [57505] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57506] (20 PDB entries)
   Uniprot P15692 40-133

8. Domain d1mkgd_: 1mkg D: [79237]
   disulfide deficient mutant
   mutant

Details for d1mkgd_

PDB Entry: 1mkg, 2.5 Å

PDB Description: disulfide deficient mutant of vascular endothelial growth factor a (c57a and c102a)

PDB Compounds: (D:) Vascular Endothelial Growth Factor A

SCOPe Domain Sequences for d1mkgd_:

Sequence; same for both SEQRES and ATOM records:

>d1mkgd_ g.17.1.1 (D:) Vascular endothelial growth factor, VEGF {Human (Homo sapiens) [TaxId: 9606]}
vvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmraggccndeglecvptee
snitmqimrikphqgqhigemsflqhnkaecrpk

Timeline for d1mkgd_:

• d1mkgd_ first appeared in SCOP 1.63
  
• d1mkgd_ appears in SCOPe 2.05
  
• d1mkgd_ appears in SCOPe 2.07
  
• d1mkgd_ appears in the current release, SCOPe 2.08