SCOP 1.71: Domain d1m7nb_: 1m7n B:

Lineage for d1m7nb_ (1m7n B:)

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (60 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Insulin-like growth factor 1 receptor [69825] (1 species)
   PTK group; InsR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [69826] (4 PDB entries)

8. Domain d1m7nb_: 1m7n B: [78739]

Details for d1m7nb_

PDB Entry: 1m7n, 2.7 Å

PDB Description: Crystal Structure of Unactivated APO Insulin-like Growth Factor-1 Receptor Kinase Domain

SCOP Domain Sequences for d1m7nb_:

Sequence, based on SEQRES records:

>d1m7nb_ d.144.1.7 (B:) Insulin-like growth factor 1 receptor {Human (Homo sapiens)}
saadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasm
rerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemenn
pvlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiy
etdyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqv
lrfvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyy
seenk

Sequence, based on observed residues (ATOM records):

>d1m7nb_ d.144.1.7 (B:) Insulin-like growth factor 1 receptor {Human (Homo sapiens)}
saadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasm
rerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpvlapp
slskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyr
kggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvme
gglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

Timeline for d1m7nb_:

• d1m7nb_ first appeared in SCOP 1.63
  
• d1m7nb_ appears in SCOP 1.69
  
• d1m7nb_ appears in SCOP 1.73
  
• d1m7nb_ appears in the current release, SCOPe 2.08