SCOPe 2.03: Domain d1m0wb2: 1m0w B:1005-1210,B:1324-1491

Lineage for d1m0wb2 (1m0w B:1005-1210,B:1324-1491)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.142: ATP-grasp [56058] (2 superfamilies)
   Consists of two subdomains with different alpha+beta folds
   shares functional and structural similarities with the PIPK and protein kinase superfamilies

4. Superfamily d.142.1: Glutathione synthetase ATP-binding domain-like [56059] (10 families)

5. Family d.142.1.6: Eukaryotic glutathione synthetase ATP-binding domain [56088] (1 protein)
   circularly permuted version of prokaryotic enzyme
   automatically mapped to Pfam PF03917

6. Protein Eukaryotic glutathione synthetase ATP-binding domain [56089] (2 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [82788] (2 PDB entries)

8. Domain d1m0wb2: 1m0w B:1005-1210,B:1324-1491 [78366]
   Other proteins in same PDB: d1m0wa1, d1m0wb1
   complexed with 3gc, anp, mg, so4

Details for d1m0wb2

PDB Entry: 1m0w, 1.8 Å

PDB Description: yeast glutathione synthase bound to gamma-glutamyl-cysteine, amp-pnp and 2 magnesium ions

PDB Compounds: (B:) glutathione synthetase

SCOPe Domain Sequences for d1m0wb2:

Sequence, based on SEQRES records:

>d1m0wb2 d.142.1.6 (B:1005-1210,B:1324-1491) Eukaryotic glutathione synthetase ATP-binding domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
ppskdqlneliqevnqwaitnglsmyppkfeenpsnasvspvtiyptpiprkcfdeavqi
qpvfnelyaritqdmaqpdsylhkttealalsdseftgklwslylatlksaqykkqnfrl
gifrsdylidkkkgteqikqvefntvsvsfaglsekvdrlhsylnrankydpkgpiyndq
nmvisdsgyllskalakavesyksqqXkkiqqlltdegvlgkyisdaekkssllktfvki
yplddtklgregkrlalsepskyvlkpqregggnnvykenipnflkgieerhwdayilme
liepelnenniilrdnksynepiiselgiygcvlfndeqvlsnefsgsllrskfntsneg
gvaagfgcldsiily

Sequence, based on observed residues (ATOM records):

>d1m0wb2 d.142.1.6 (B:1005-1210,B:1324-1491) Eukaryotic glutathione synthetase ATP-binding domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
ppskdqlneliqevnqwaitnglsmyppkfeenpsnasvspvtiyptpiprkcfdeavqi
qpvfnelyaritqdmaqpdsylhkttealalsdseftgklwslylatlksaqykkqnfrl
gifrsdylidkkkgteqikqvefntvsvsfaglsekvdrlhsylnrankydpkgpiyndq
nmvisdsgyllskalakavesyksqqXkkiqqlltdegvlgkyisdaekkssllktfvki
yplddtklgregkrlalsepskyvlkpqregnnvykenipnflkgieerhwdayilmeli
epelnenniilrdnksynepiiselgiygcvlfndeqvlsnefsgsllrskfntsneggv
aagfgcldsiily

Timeline for d1m0wb2:

• d1m0wb2 first appeared in SCOP 1.63
  
• d1m0wb2 appears in SCOPe 2.02
  
• d1m0wb2 appears in SCOPe 2.04
  
• d1m0wb2 appears in the current release, SCOPe 2.08