Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds) |
Fold e.8: DNA/RNA polymerases [56671] (1 superfamily) divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members |
Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families) "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain |
Family e.8.1.2: Reverse transcriptase [56686] (2 proteins) |
Protein HIV-1 reverse transcriptase [56689] (2 species) |
Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (111 PDB entries) Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595 Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595 |
Domain d1lw2b_: 1lw2 B: [78253] Other proteins in same PDB: d1lw2a1 complexed with csd, po4, u05; mutant |
PDB Entry: 1lw2 (more details), 3 Å
SCOP Domain Sequences for d1lw2b_:
Sequence, based on SEQRES records: (download)
>d1lw2b_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]} tvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkk dstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrk ytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymdd lyvgsdleigqhrtkieelrqhllrwglytpdkkhqkeppflwmgyelhpdkwtvqpivl pekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaen reilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvk qlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklw yq
>d1lw2b_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]} tvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkk dstkwrklvdfrelnkrtqdfwiphpaglkkkksvtvldvgdayfsvpldedfrkytaft ipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgs dleigqhrtkieelrqhllrwglytkeppflwmgyelhpdkwtvqpivlpekdswtvndi qklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgv yydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyartndvkqlteavqkittesivi wgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
Timeline for d1lw2b_: