SCOP 1.75: Domain d1lo5a1: 1lo5 A:82-182

Lineage for d1lo5a1 (1lo5 A:82-182)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Class II MHC alpha chain, C-terminal domain [88618] (6 species)

7. Species Human (Homo sapiens), HLA-DR group [TaxId:9606] [88621] (29 PDB entries)
   Uniprot P01903 28-207
   probably orthologous to the mouse I-E group

8. Domain d1lo5a1: 1lo5 A:82-182 [78116]
   Other proteins in same PDB: d1lo5a2, d1lo5b1, d1lo5b2, d1lo5d1, d1lo5d2
   mutant

Details for d1lo5a1

PDB Entry: 1lo5, 3.2 Å

PDB Description: crystal structure of the d227a variant of staphylococcal enterotoxin a in complex with human mhc class ii

PDB Compounds: (A:) hla class II histocompatibility antigen, dr alpha chain

SCOP Domain Sequences for d1lo5a1:

Sequence; same for both SEQRES and ATOM records:

>d1lo5a1 b.1.1.2 (A:82-182) Class II MHC alpha chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
itnvppevtvltnspvelrepnvlicfidkftppvvnvtwlrngkpvttgvsetvflpre
dhlfrkfhylpflpstedvydcrvehwgldepllkhwefda

Timeline for d1lo5a1:

• d1lo5a1 first appeared in SCOP 1.63
  
• d1lo5a1 appears in SCOP 1.73
  
• d1lo5a1 appears in SCOPe 2.01
  
• d1lo5a1 appears in the current release, SCOPe 2.08