SCOP 1.73: Domain d1l7tl1: 1l7t L:1-112

Lineage for d1l7tl1 (1l7t L:1-112)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (29 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (127 PDB entries)

8. Domain d1l7tl1: 1l7t L:1-112 [77801]
   Other proteins in same PDB: d1l7th1, d1l7th2, d1l7tl2
   part of anti-testosterone Fab 77

Details for d1l7tl1

PDB Entry: 1l7t, 2.1 Å

PDB Description: crystal structure analysis of the anti-testosterone fab fragment

PDB Compounds: (L:) anti-testosterone (light chain)

SCOP Domain Sequences for d1l7tl1:

Sequence; same for both SEQRES and ATOM records:

>d1l7tl1 b.1.1.1 (L:1-112) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1 [TaxId: 10090]}
dvvvtqtplslpvslgdqasiscrssevivtrngytpiewylqkpgqspklliykaykrf
pgvpdrfsgsgsgtdftlkisrveaedlgvyycfdgstvppkfgggtkleik

Timeline for d1l7tl1:

• d1l7tl1 first appeared in SCOP 1.63
  
• d1l7tl1 appears in SCOP 1.71
  
• d1l7tl1 appears in SCOP 1.75
  
• d1l7tl1 appears in the current release, SCOPe 2.08