SCOP 1.75: Domain d1jvsa3: 1jvs A:126-274

Lineage for d1jvsa3 (1jvs A:126-274)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.81: FwdE/GAPDH domain-like [55346] (4 superfamilies)
   core: alpha-beta-alpha-beta(3); mixed sheet: 2134, strand 2 is parallel to strand 1

4. Superfamily d.81.1: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55347] (5 families)
   N-terminal domain is the classic Rossmann-fold

5. Family d.81.1.3: Dihydrodipicolinate reductase-like [55368] (6 proteins)

6. Protein 1-deoxy-D-xylulose-5-phosphate reductoisomerase [69770] (2 species)

7. Species Escherichia coli [TaxId:562] [69771] (11 PDB entries)
   Uniprot P45568

8. Domain d1jvsa3: 1jvs A:126-274 [77189]
   Other proteins in same PDB: d1jvsa1, d1jvsa2, d1jvsb1, d1jvsb2

Details for d1jvsa3

PDB Entry: 1jvs, 2.2 Å

PDB Description: crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase; a target enzyme for antimalarial drugs

PDB Compounds: (A:) 1-deoxy-D-xylulose 5-phosphate reductoisomerase

SCOP Domain Sequences for d1jvsa3:

Sequence; same for both SEQRES and ATOM records:

>d1jvsa3 d.81.1.3 (A:126-274) 1-deoxy-D-xylulose-5-phosphate reductoisomerase {Escherichia coli [TaxId: 562]}
slvtcgrlfmdavkqskaqllpvdsehnaifqslpqpiqhnlgyadleqngvvsilltgs
ggpfretplrdlatmtpdqacrhpnwsmgrkisvdsatmmnkgleyiearwlfnasasqm
evlihpqsvihsmvryqdgsvlaqlgepd

Timeline for d1jvsa3:

• d1jvsa3 first appeared in SCOP 1.63
  
• d1jvsa3 appears in SCOP 1.73
  
• d1jvsa3 appears in SCOPe 2.01
  
• d1jvsa3 appears in the current release, SCOPe 2.08