Lineage for d1ivoa2 (1ivo A:312-480)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1834683Fold c.10: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [52046] (3 superfamilies)
    2 curved layers, a/b; parallel beta-sheet; order 1234...N; there are sequence similarities between different superfamilies
  4. 1834752Superfamily c.10.2: L domain-like [52058] (9 families) (S)
    less regular structure consisting of variable repeats
  5. 1834828Family c.10.2.5: L domain [52071] (6 proteins)
    this is a repeat family; one repeat unit is 1n8z C:42-66 found in domain
  6. 1834829Protein EGF receptor extracellular domain [82326] (1 species)
  7. 1834830Species Human (Homo sapiens) [TaxId:9606] [82327] (7 PDB entries)
  8. 1834851Domain d1ivoa2: 1ivo A:312-480 [76846]
    Other proteins in same PDB: d1ivoa3, d1ivoa4, d1ivob3, d1ivob4, d1ivoc_, d1ivod_
    L1 and L2 domains; complexed with EGF
    complexed with nag

Details for d1ivoa2

PDB Entry: 1ivo (more details), 3.3 Å

PDB Description: crystal structure of the complex of human epidermal growth factor and receptor extracellular domains.
PDB Compounds: (A:) Epidermal growth factor receptor

SCOPe Domain Sequences for d1ivoa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ivoa2 c.10.2.5 (A:312-480) EGF receptor extracellular domain {Human (Homo sapiens) [TaxId: 9606]}
vcngigigefkdslsinatnikhfknctsisgdlhilpvafrgdsfthtppldpqeldil
ktvkeitgflliqawpenrtdlhafenleiirgrtkqhgqfslavvslnitslglrslke
isdgdviisgnknlcyantinwkklfgtsgqktkiisnrgensckatgq

SCOPe Domain Coordinates for d1ivoa2:

Click to download the PDB-style file with coordinates for d1ivoa2.
(The format of our PDB-style files is described here.)

Timeline for d1ivoa2: