SCOPe 2.03: Domain d1h3wm2: 1h3w M:342-443

Lineage for d1h3wm2 (1h3w M:342-443)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma [88589] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88590] (33 PDB entries)
   Uniprot P01857 #118-327 ! Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region

8. Domain d1h3wm2: 1h3w M:342-443 [76666]
   Other proteins in same PDB: d1h3wm1
   part of a Fc

Details for d1h3wm2

PDB Entry: 1h3w, 2.85 Å

PDB Description: structural analysis of human igg-fc glycoforms reveals a correlation between glycosylation and structural integrity

PDB Compounds: (M:) Ig gamma-1 chain C region

SCOPe Domain Sequences for d1h3wm2:

Sequence; same for both SEQRES and ATOM records:

>d1h3wm2 b.1.1.2 (M:342-443) Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma {Human (Homo sapiens) [TaxId: 9606]}
qprepqvytlppsreemtknqvsltclvkgfypsdiavewesngqpennykttppvldsd
gsfflyskltvdksrwqqgnvfscsvmhealhnhytqkslsl

Timeline for d1h3wm2:

• d1h3wm2 first appeared in SCOP 1.63
  
• d1h3wm2 appears in SCOPe 2.02
  
• d1h3wm2 appears in SCOPe 2.04
  
• d1h3wm2 appears in the current release, SCOPe 2.08