SCOP 1.75: Domain d1h3tb2: 1h3t B:342-444

Lineage for d1h3tb2 (1h3t B:342-444)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma [88589] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88590] (28 PDB entries)
   Uniprot P01857 #118-327
   Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region
   Uniprot P01857 #118-327 ! Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region

8. Domain d1h3tb2: 1h3t B:342-444 [76656]
   Other proteins in same PDB: d1h3ta1, d1h3tb1
   part of a Fc
   complexed with afl, bma, nag

Details for d1h3tb2

PDB Entry: 1h3t, 2.4 Å

PDB Description: crystal structure of the human igg1 fc-fragment,glycoform (mn2f)2

PDB Compounds: (B:) Ig gamma-1 chain C region

SCOP Domain Sequences for d1h3tb2:

Sequence; same for both SEQRES and ATOM records:

>d1h3tb2 b.1.1.2 (B:342-444) Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma {Human (Homo sapiens) [TaxId: 9606]}
qprepqvytlppsreemtknqvsltclvkgfypsdiavewesngqpennykttppvldsd
gsfflyskltvdksrwqqgnvfscsvmhealhnhytqkslsls

Timeline for d1h3tb2:

• d1h3tb2 first appeared in SCOP 1.63
  
• d1h3tb2 appears in SCOP 1.73
  
• d1h3tb2 appears in SCOPe 2.01
  
• d1h3tb2 appears in the current release, SCOPe 2.08