SCOPe 2.08: Domain d1h2tc3: 1h2t C:481-790

Lineage for d1h2tc3 (1h2t C:481-790)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (28 families)

5. Family a.118.1.14: MIF4G domain-like [100908] (6 proteins)
   duplication: family members contains 2 or more structurally similar domains of this fold connected by unstructured linkers
   this is a repeat family; one repeat unit is 1hu3 A:905-942 found in domain

6. Protein CBP80, 80KDa nuclear cap-binding protein [63606] (1 species)
   contains three domains of this fold connected with long linkers

7. Species Human (Homo sapiens) [TaxId:9606] [63607] (6 PDB entries)

8. Domain d1h2tc3: 1h2t C:481-790 [76582]
   Other proteins in same PDB: d1h2tz_
   protein/RNA complex; complexed with 7mg, gdp

Details for d1h2tc3

PDB Entry: 1h2t, 2.1 Å

PDB Description: structure of the human nuclear cap-binding-complex (cbc) in complex with a cap analogue m7gpppg

PDB Compounds: (C:) 80 kda nuclear cap binding protein

SCOPe Domain Sequences for d1h2tc3:

Sequence, based on SEQRES records:

>d1h2tc3 a.118.1.14 (C:481-790) CBP80, 80KDa nuclear cap-binding protein {Human (Homo sapiens) [TaxId: 9606]}
ptciykygdessnslpghsvalclavafkskatndeifsilkdvpnpnqdddddegfsfn
plkievfvqtllhlaaksfshsfsalakfhevfktlaesdegklhvlrvmfevwrnhpqm
iavlvdkmirtqivdcaavanwifsselsrdftrlfvweilhstirkmnkhvgaqseqkn
lflvifqrfimiltehlvrcetdgtsvltpwykncierlqqiflqhhqiiqqymvtlenl
lftaeldphilavfqqfcalqa

Sequence, based on observed residues (ATOM records):

>d1h2tc3 a.118.1.14 (C:481-790) CBP80, 80KDa nuclear cap-binding protein {Human (Homo sapiens) [TaxId: 9606]}
ptciykygdessnslpghsvalclavafkskatndeifsilkdvpnpsfnplkievfvqt
llhlaaksfshsfsalakfhevfktlaesdegklhvlrvmfevwrnhpqmiavlvdkmir
tqivdcaavanwifsselsrdftrlfvweilhstirkmnkhvgaqseqknlflvifqrfi
miltehlvrcetdgtsvltpwykncierlqqiflqhhqiiqqymvtlenllftaeldphi
lavfqqfcalqa

Timeline for d1h2tc3:

• d1h2tc3 first appeared in SCOP 1.63
  
• d1h2tc3 appears in SCOPe 2.07