Lineage for d1h2ka_ (1h2k A:)

  1. Root: SCOPe 2.05
  2. 1755445Class b: All beta proteins [48724] (176 folds)
  3. 1807020Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 1807787Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 1807938Family b.82.2.6: Hypoxia-inducible factor HIF ihhibitor (FIH1) [82194] (1 protein)
  6. 1807939Protein Hypoxia-inducible factor HIF ihhibitor (FIH1) [82195] (1 species)
  7. 1807940Species Human (Homo sapiens) [TaxId:9606] [82196] (28 PDB entries)
  8. 1807941Domain d1h2ka_: 1h2k A: [76572]
    Other proteins in same PDB: d1h2ks_
    complex with HIF-1 alpha fragment peptide
    complexed with fe2, oga, so4

Details for d1h2ka_

PDB Entry: 1h2k (more details), 2.15 Å

PDB Description: factor inhibiting hif-1 alpha in complex with hif-1 alpha fragment peptide
PDB Compounds: (A:) factor inhibiting hif1

SCOPe Domain Sequences for d1h2ka_:

Sequence, based on SEQRES records: (download)

>d1h2ka_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]}
epreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlvypal
kwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkfhefveklqd
iqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligmegn
vtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyerfpn
fqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkrieyplkahq
kvaimrniekmlgealgnpqevgpllntmikgryn

Sequence, based on observed residues (ATOM records): (download)

>d1h2ka_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]}
epreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlvypal
kwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkfhefveklqd
iqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligmegn
vtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyerfpn
fqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpeyplkahqkva
imrniekmlgealgnpqevgpllntmikgryn

SCOPe Domain Coordinates for d1h2ka_:

Click to download the PDB-style file with coordinates for d1h2ka_.
(The format of our PDB-style files is described here.)

Timeline for d1h2ka_: