Class d: Alpha and beta proteins (a+b) [53931] (286 folds) |
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily) consists of two alpha+beta domains, C-terminal domain is mostly alpha helical |
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) shares functional and structural similarities with the ATP-grasp fold and PIPK |
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (60 proteins) members organized in the groups and subfamiles specified by the comments |
Protein Cyclin-dependent PK, CDK2 [88855] (2 species) CMGC group; CDKs subfamily; serine/threonine kinase |
Species Human (Homo sapiens) [TaxId:9606] [88856] (80 PDB entries) |
Domain d1h25c_: 1h25 C: [76525] Other proteins in same PDB: d1h25b1, d1h25b2, d1h25d1, d1h25d2 complex with cyclin and an 11-residue recruitment peptide from retinoblastoma-associated protein complexed with tpo |
PDB Entry: 1h25 (more details), 2.5 Å
SCOP Domain Sequences for d1h25c_:
Sequence, based on SEQRES records: (download)
>d1h25c_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens)} smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpv
>d1h25c_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens)} smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdvvpp ldedgrsllsqmlhydpnkrisakaalahpffqdvtkpv
Timeline for d1h25c_: