Lineage for Species: Escherichia coli

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 242757Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 242758Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (4 families) (S)
    both pyridine (Pyr)- and pyrophosphate (PP)-binding modules have this fold
    conserved core consists of two Pyr and two PP-modules and binds two coenzyme molecules
  5. 242840Family c.36.1.2: TK-like THDP-binding domains [52528] (2 proteins)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 242841Protein Pyruvate dehydrogenase E1 component, PP and Pyr modules [75185] (1 species)
    E1A and E1B fused together in a single-chain protein
  7. 242842Species Escherichia coli [TaxId:562] [75186] (1 PDB entry)

PDB entry in Species: Escherichia coli:

More info for Species Escherichia coli [TaxId:562] from c.36.1.2 Pyruvate dehydrogenase E1 component, PP and Pyr modules

Timeline for Species Escherichia coli [TaxId:562] from c.36.1.2 Pyruvate dehydrogenase E1 component, PP and Pyr modules:

  • Species Escherichia coli [TaxId:562] from c.36.1.2 Pyruvate dehydrogenase E1 component, PP and Pyr modules first appeared in SCOP 1.61, called Species Escherichia coli [TaxId:562] from c.36.1.2 Pyruvate dehydrogenase E1 component
  • Species Escherichia coli [TaxId:562] from c.36.1.2 Pyruvate dehydrogenase E1 component, PP and Pyr modules does not appear in SCOP 1.65