SCOPe 2.08: Protein: Myo-inositol 1-phosphate synthase

Lineage for Protein: Myo-inositol 1-phosphate synthase

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)
Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
family members also share a common alpha+beta fold in C-terminal domain
Protein Myo-inositol 1-phosphate synthase [75105] (4 species)

Species:

Archaeoglobus fulgidus [TaxId:2234] [110418] (3 PDB entries)
Uniprot O28480

Domains for 1u1i:

Domain d1u1ia1: 1u1i A:1-227,A:333-392 [107582]
Other proteins in same PDB: d1u1ia2, d1u1ib2, d1u1ic2, d1u1id2
complexed with k, nad, po4
has additional insertions and/or extensions that are not grouped together

Domain d1u1ib1: 1u1i B:401-627,B:733-792 [107584]
Other proteins in same PDB: d1u1ia2, d1u1ib2, d1u1ic2, d1u1id2
complexed with k, nad, po4
has additional insertions and/or extensions that are not grouped together

Domain d1u1ic1: 1u1i C:801-1027,C:1133-1192 [107586]
Other proteins in same PDB: d1u1ia2, d1u1ib2, d1u1ic2, d1u1id2
complexed with k, nad, po4
has additional insertions and/or extensions that are not grouped together

Domain d1u1id1: 1u1i D:1201-1427,D:1533-1592 [107588]
Other proteins in same PDB: d1u1ia2, d1u1ib2, d1u1ic2, d1u1id2
complexed with k, nad, po4
has additional insertions and/or extensions that are not grouped together

Domain for 3qvs:

Domain d3qvsa1: 3qvs A:1-227,A:333-392 [215457]
Other proteins in same PDB: d3qvsa2
automated match to d1u1ia1
complexed with gol, na, nad, pg4, po4
has additional insertions and/or extensions that are not grouped together

Domain for 3qvt:

Domain d3qvta1: 3qvt A:1-227,A:333-392 [215459]
Other proteins in same PDB: d3qvta2
automated match to d1u1ia1
complexed with gol, kpg, na, nai, pg4, po4
has additional insertions and/or extensions that are not grouped together

Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [75107] (9 PDB entries)
Uniprot P11986
1. Domains for 1jkf:
  1. Domain d1jkfa1: 1jkf A:11-322,A:438-533 [71700]
    Other proteins in same PDB: d1jkfa2, d1jkfb2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
  2. Domain d1jkfb1: 1jkf B:10-322,B:438-533 [71702]
    Other proteins in same PDB: d1jkfa2, d1jkfb2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
2. Domains for 1jki:
  1. Domain d1jkia1: 1jki A:9-322,A:438-533 [71704]
    Other proteins in same PDB: d1jkia2, d1jkib2
    complexed with dg6, nai, nh4
    has additional subdomain(s) that are not in the common domain
  2. Domain d1jkib1: 1jki B:10-322,B:438-533 [71706]
    Other proteins in same PDB: d1jkia2, d1jkib2
    complexed with dg6, nai, nh4
    has additional subdomain(s) that are not in the common domain
3. Domains for 1la2:
  1. Domain d1la2a1: 1la2 A:10-322,A:438-533 [73773]
    Other proteins in same PDB: d1la2a2, d1la2b2, d1la2c2, d1la2d2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
  2. Domain d1la2b1: 1la2 B:10-322,B:438-533 [73775]
    Other proteins in same PDB: d1la2a2, d1la2b2, d1la2c2, d1la2d2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
  3. Domain d1la2c1: 1la2 C:10-322,C:438-533 [73777]
    Other proteins in same PDB: d1la2a2, d1la2b2, d1la2c2, d1la2d2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
  4. Domain d1la2d1: 1la2 D:10-322,D:438-533 [73779]
    Other proteins in same PDB: d1la2a2, d1la2b2, d1la2c2, d1la2d2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
4. Domains for 1p1f:
  1. Domain d1p1fa1: 1p1f A:9-322,A:438-533 [87671]
    Other proteins in same PDB: d1p1fa2, d1p1fb2
    has additional subdomain(s) that are not in the common domain
  2. Domain d1p1fb1: 1p1f B:9-322,B:438-533 [87673]
    Other proteins in same PDB: d1p1fa2, d1p1fb2
    has additional subdomain(s) that are not in the common domain
5. Domains for 1p1h:
  1. Domain d1p1ha1: 1p1h A:10-322,A:438-533 [87675]
    Other proteins in same PDB: d1p1ha2, d1p1hb2, d1p1hc2, d1p1hd2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
  2. Domain d1p1hb1: 1p1h B:10-322,B:438-533 [87677]
    Other proteins in same PDB: d1p1ha2, d1p1hb2, d1p1hc2, d1p1hd2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
  3. Domain d1p1hc1: 1p1h C:10-322,C:438-533 [87679]
    Other proteins in same PDB: d1p1ha2, d1p1hb2, d1p1hc2, d1p1hd2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
  4. Domain d1p1hd1: 1p1h D:10-322,D:438-533 [87681]
    Other proteins in same PDB: d1p1ha2, d1p1hb2, d1p1hc2, d1p1hd2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
6. Domains for 1p1i:
  1. Domain d1p1ia1: 1p1i A:9-322,A:438-533 [87683]
    Other proteins in same PDB: d1p1ia2, d1p1ib2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
  2. Domain d1p1ib1: 1p1i B:10-322,B:438-533 [87685]
    Other proteins in same PDB: d1p1ia2, d1p1ib2
    complexed with nad
    has additional subdomain(s) that are not in the common domain
7. Domains for 1p1j:
  1. Domain d1p1ja1: 1p1j A:9-322,A:438-533 [87687]
    Other proteins in same PDB: d1p1ja2, d1p1jb2
    complexed with gol, nai, po4
    has additional subdomain(s) that are not in the common domain
  2. Domain d1p1jb1: 1p1j B:10-322,B:438-533 [87689]
    Other proteins in same PDB: d1p1ja2, d1p1jb2
    complexed with gol, nai, po4
    has additional subdomain(s) that are not in the common domain
8. Domains for 1p1k:
  1. Domain d1p1ka1: 1p1k A:9-322,A:438-533 [87691]
    Other proteins in same PDB: d1p1ka2, d1p1kb2
    complexed with nai
    has additional subdomain(s) that are not in the common domain
  2. Domain d1p1kb1: 1p1k B:10-322,B:438-533 [87693]
    Other proteins in same PDB: d1p1ka2, d1p1kb2
    complexed with nai
    has additional subdomain(s) that are not in the common domain
9. Domains for 1rm0:
  1. Domain d1rm0a1: 1rm0 A:10-322,A:438-533 [104990]
    Other proteins in same PDB: d1rm0a2, d1rm0b2
    complexed with d6p, mn, nai
    has additional subdomain(s) that are not in the common domain
  2. Domain d1rm0b1: 1rm0 B:10-322,B:438-533 [104992]
    Other proteins in same PDB: d1rm0a2, d1rm0b2
    complexed with d6p, mn, nai
    has additional subdomain(s) that are not in the common domain
Mycobacterium tuberculosis [TaxId:1773] [75106] (1 PDB entry)
- Domain for 1gr0:
  - Domain d1gr0a1: 1gr0 A:14-200,A:312-367 [70379]
    Other proteins in same PDB: d1gr0a2
    complexed with cac, nad, zn
    has additional insertions and/or extensions that are not grouped together

Nematode (Caenorhabditis elegans) [TaxId:6239] [110419] (1 PDB entry)
Uniprot Q18664

Domain for 1vko:

Domain d1vkoa1: 1vko A:11-314,A:429-521 [108684]
Other proteins in same PDB: d1vkoa2
Structural genomics target
complexed with cl, iod, k, nad, pop
has additional subdomain(s) that are not in the common domain

More info for Protein Myo-inositol 1-phosphate synthase from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

Timeline for Protein Myo-inositol 1-phosphate synthase from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain:

Protein Myo-inositol 1-phosphate synthase from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain first appeared in SCOP 1.61
Protein Myo-inositol 1-phosphate synthase from c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain appears in SCOPe 2.07