SCOPe 2.08: Domain d1m54b_: 1m54 B:

Lineage for d1m54b_ (1m54 B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.79: Tryptophan synthase beta subunit-like PLP-dependent enzymes [53685] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 3214

4. Superfamily c.79.1: Tryptophan synthase beta subunit-like PLP-dependent enzymes [53686] (2 families)

5. Family c.79.1.1: Tryptophan synthase beta subunit-like PLP-dependent enzymes [53687] (9 proteins)

6. Protein Cystathionine beta-synthase [64174] (1 species)
   PLP-dependent hemoprotein

7. Species Human (Homo sapiens) [TaxId:9606] [64175] (3 PDB entries)

8. Domain d1m54b_: 1m54 B: [74464]
   complexed with hem, plp

Details for d1m54b_

PDB Entry: 1m54, 2.9 Å

PDB Description: cystathionine-beta synthase: reduced vicinal thiols

PDB Compounds: (B:) cystathionine beta-synthase

SCOPe Domain Sequences for d1m54b_:

Sequence, based on SEQRES records:

>d1m54b_ c.79.1.1 (B:) Cystathionine beta-synthase {Human (Homo sapiens) [TaxId: 9606]}
rpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkce
llakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgyr
ciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnshildqyr
nasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpeg
silaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegl
lcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflkeed

Sequence, based on observed residues (ATOM records):

>d1m54b_ c.79.1.1 (B:) Cystathionine beta-synthase {Human (Homo sapiens) [TaxId: 9606]}
rpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkce
llakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgyr
ciivmpekmssekvdvlralgaeivrtptshvgvawrlkneipnshildqyrnasnplah
ydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilaepee
lnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggsags
tvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgfeed

Timeline for d1m54b_:

• d1m54b_ first appeared in SCOP 1.61
  
• d1m54b_ appears in SCOPe 2.07