SCOP 1.75: Domain d1lb1g1: 1lb1 G:624-818

Lineage for d1lb1g1 (1lb1 G:624-818)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.87: DBL homology domain (DH-domain) [48064] (1 superfamily)
   multihelical; core: 5-helical bundle

4. Superfamily a.87.1: DBL homology domain (DH-domain) [48065] (1 family)

5. Family a.87.1.1: DBL homology domain (DH-domain) [48066] (10 proteins)
   Pfam PF00621

6. Protein Dbl's big sister, Dbs [74743] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [74744] (4 PDB entries)
   Uniprot Q64096 624-958 # 98% sequence identity; the rat sequence Q63406 region 499-833 is 100% identical to the PDB sequence

8. Domain d1lb1g1: 1lb1 G:624-818 [73793]
   Other proteins in same PDB: d1lb1a2, d1lb1b_, d1lb1c2, d1lb1d_, d1lb1e2, d1lb1f_, d1lb1g2, d1lb1h_
   mutant

Details for d1lb1g1

PDB Entry: 1lb1, 2.81 Å

PDB Description: crystal structure of the dbl and pleckstrin homology domains of dbs in complex with rhoa

PDB Compounds: (G:) guanine nucleotide exchange factor dbs

SCOP Domain Sequences for d1lb1g1:

Sequence; same for both SEQRES and ATOM records:

>d1lb1g1 a.87.1.1 (G:624-818) Dbl's big sister, Dbs {Mouse (Mus musculus) [TaxId: 10090]}
eeeeslailrrhvmnelldterayveellcvlegyaaemdnplmahlistglqnkknilf
gnmeeiyhfhnriflrelescidcpelvgrcflermeefqiyekycqnkprseslwrqcs
dcpffqecqkkldhklsldsyllkpvqritkyqlllkemlkyskhcegaedlqealssil
gilkavndsmhliai

Timeline for d1lb1g1:

• d1lb1g1 first appeared in SCOP 1.61
  
• d1lb1g1 appears in SCOP 1.73
  
• d1lb1g1 appears in SCOPe 2.01
  
• d1lb1g1 appears in the current release, SCOPe 2.08