SCOPe 2.05: Domain d1kyqa1: 1kyq A:1-150

Lineage for d1kyqa1 (1kyq A:1-150)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.11: Siroheme synthase N-terminal domain-like [75110] (2 proteins)

6. Protein Bifunctional dehydrogenase/ferrochelatase Met8p, N-terminal domain [75111] (1 species)
   involved in siroheme synthesis

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [75112] (1 PDB entry)

8. Domain d1kyqa1: 1kyq A:1-150 [73281]
   Other proteins in same PDB: d1kyqa2, d1kyqb2, d1kyqc2
   complexed with nad

Details for d1kyqa1

PDB Entry: 1kyq, 2.2 Å

PDB Description: Met8p: A bifunctional NAD-dependent dehydrogenase and ferrochelatase involved in siroheme synthesis.

PDB Compounds: (A:) Siroheme biosynthesis protein MET8

SCOPe Domain Sequences for d1kyqa1:

Sequence, based on SEQRES records:

>d1kyqa1 c.2.1.11 (A:1-150) Bifunctional dehydrogenase/ferrochelatase Met8p, N-terminal domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mvkslqlahqlkdkrilligggevgltrlyklmptgckltlvspdlhksiipkfgkfiqn
kdqpdyredakrfinpnwdptkneiyeyirsdfkdeyldlenendawyiimtcipdhpes
ariyhlckerfgkqqlvnvadkpdlcdfyf

Sequence, based on observed residues (ATOM records):

>d1kyqa1 c.2.1.11 (A:1-150) Bifunctional dehydrogenase/ferrochelatase Met8p, N-terminal domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mvkslqlahqlkdkrilligggevgltrlyklmptgckltlvspdlhksiipkfgkfiqk
rfinpnwdptkneiyeyirsdfkdeyldlenendawyiimtcipdhpesariyhlckerf
gkqqlvnvadkpdlcdfyf

Timeline for d1kyqa1:

• d1kyqa1 first appeared in SCOP 1.61
  
• d1kyqa1 appears in SCOPe 2.04
  
• d1kyqa1 appears in SCOPe 2.06
  
• d1kyqa1 appears in the current release, SCOPe 2.08