SCOP 1.73: Domain d1ki1d2: 1ki1 D:1439-1580

Lineage for d1ki1d2 (1ki1 D:1439-1580)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.55: PH domain-like barrel [50728] (2 superfamilies)
   barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix

4. Superfamily b.55.1: PH domain-like [50729] (12 families)

5. Family b.55.1.1: Pleckstrin-homology domain (PH domain) [50730] (43 proteins)
   Pfam PF00169

6. Protein GEF of intersectin [74991] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [74992] (1 PDB entry)

8. Domain d1ki1d2: 1ki1 D:1439-1580 [72501]
   Other proteins in same PDB: d1ki1a_, d1ki1b1, d1ki1c_, d1ki1d1
   complexed with so4; mutant

Details for d1ki1d2

PDB Entry: 1ki1, 2.3 Å

PDB Description: guanine nucleotide exchange region of intersectin in complex with cdc42

PDB Compounds: (D:) intersectin long form

SCOP Domain Sequences for d1ki1d2:

Sequence, based on SEQRES records:

>d1ki1d2 b.55.1.1 (D:1439-1580) GEF of intersectin {Human (Homo sapiens) [TaxId: 9606]}
hvqceglseqlvfnsvtnclgprkflhsgklykaknnkelygflfndfllltqitkplgs
sgtdkvfspksnlqymyktpiflnevlvklptdpsgdepifhishidrvytlraesiner
tawvqkikaaselyietekkkr

Sequence, based on observed residues (ATOM records):

>d1ki1d2 b.55.1.1 (D:1439-1580) GEF of intersectin {Human (Homo sapiens) [TaxId: 9606]}
hvqceglseqlvfnsvtnclgprkflhsgklykaknnkelygflfndfllltqitkpkvf
spksnlqymyktpiflnevlvklptdpsgdfhishidrvytlraesinertawvqkikaa
selyietekkkr

Timeline for d1ki1d2:

• d1ki1d2 first appeared in SCOP 1.61
  
• d1ki1d2 appears in SCOP 1.71
  
• d1ki1d2 appears in SCOP 1.75
  
• d1ki1d2 appears in the current release, SCOPe 2.08