SCOP 1.63: Domain d1k9ae3: 1k9a E:178-450

Lineage for d1k9ae3 (1k9a E:178-450)

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.2: Tyrosine kinase [56150] (15 proteins)

6. Protein Carboxyl-terminal src kinase (csk) [56164] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56165] (2 PDB entries)

8. Domain d1k9ae3: 1k9a E:178-450 [72202]
   Other proteins in same PDB: d1k9aa1, d1k9aa2, d1k9ab1, d1k9ab2, d1k9ac1, d1k9ac2, d1k9ad1, d1k9ad2, d1k9ae1, d1k9ae2, d1k9af1, d1k9af2

Details for d1k9ae3

PDB Entry: 1k9a, 2.5 Å

PDB Description: Crystal structure analysis of full-length carboxyl-terminal Src kinase at 2.5 A resolution

SCOP Domain Sequences for d1k9ae3:

Sequence, based on SEQRES records:

>d1k9ae3 d.144.1.2 (E:178-450) Carboxyl-terminal src kinase (csk) {Human (Homo sapiens)}
aaqdefyrsgwalnmkelkllqtigkgefgdvmlgdyrgnkvavkcikndataqaflaea
svmtqlrhsnlvqllgviveekgglyivteymakgslvdylrsrgrsvlggdcllkfsld
vceameylegnnfvhrdlaarnvlvsednvakvsdfgltkeasstqdtgklpvkwtapea
lrekkfstksdvwsfgillweiysfgrvpypriplkdvvprvekgykmdapdgcppavyd
vmkncwhldaatrptflqlreqlehirthelhl

Sequence, based on observed residues (ATOM records):

>d1k9ae3 d.144.1.2 (E:178-450) Carboxyl-terminal src kinase (csk) {Human (Homo sapiens)}
aaqdefyrsgwalnmkelkllqtigkgefgdvmlgdyrgnkvavkcikndataqaflaea
svmtqlrhsnlvqllgviveekgglyivteymakgslvdylrsrgrsvlggdcllkfsld
vceameylegnnfvhrdlaarnvlvsednvakvsdfgltkeasstlpvkwtapealrekk
fstksdvwsfgillweiysfgrvpypriplkdvvprvekgykmdapdgcppavydvmknc
whldaatrptflqlreqlehirthelhl

Timeline for d1k9ae3:

• d1k9ae3 first appeared in SCOP 1.61
  
• d1k9ae3 appears in SCOP 1.65
  
• d1k9ae3 appears in the current release, SCOPe 2.08