SCOPe 2.03: Domain d1k3ta2: 1k3t A:165-333

Lineage for d1k3ta2 (1k3t A:165-333)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.81: FwdE/GAPDH domain-like [55346] (4 superfamilies)
   core: alpha-beta-alpha-beta(3); mixed sheet: 2134, strand 2 is parallel to strand 1

4. Superfamily d.81.1: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55347] (5 families)
   N-terminal domain is the classic Rossmann-fold

5. Family d.81.1.1: GAPDH-like [55348] (6 proteins)
   has many additional secondary structures

6. Protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [55349] (19 species)

7. Species Trypanosoma cruzi [TaxId:5693] [75483] (5 PDB entries)

8. Domain d1k3ta2: 1k3t A:165-333 [72023]
   Other proteins in same PDB: d1k3ta1, d1k3tb1, d1k3tc1, d1k3td1
   complexed with brz

Details for d1k3ta2

PDB Entry: 1k3t, 1.95 Å

PDB Description: Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi Complexed with Chalepin, a Coumarin Derivative Inhibitor

PDB Compounds: (A:) glyceraldehyde-3-phosphate dehydrogenase

SCOPe Domain Sequences for d1k3ta2:

Sequence; same for both SEQRES and ATOM records:

>d1k3ta2 d.81.1.1 (A:165-333) Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) {Trypanosoma cruzi [TaxId: 5693]}
scttnclapivhvlvkegfgvqtglmttihsytatqktvdgvsvkdwrggraaavniips
ttgaakavgmvipstqgkltgmsfrvptpdvsvvdltftaardtsiqeidaalkraskty
mkgilgytdeelvsadfindnrssiydskatlqnnlpkerrffkivswy

Timeline for d1k3ta2:

• d1k3ta2 first appeared in SCOP 1.61
  
• d1k3ta2 appears in SCOPe 2.02
  
• d1k3ta2 appears in SCOPe 2.04
  
• d1k3ta2 appears in the current release, SCOPe 2.08