SCOP 1.67: Domain d1gq2n1: 1gq2 N:280-580

Lineage for d1gq2n1 (1gq2 N:280-580)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (11 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (10 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein Mitochondrial NAD(P)-dependent malic enzyme [51898] (3 species)
   includes C-terminal additional subdomains

7. Species Domestic pigeon (Columba livia) [TaxId:8932] [75116] (1 PDB entry)

8. Domain d1gq2n1: 1gq2 N:280-580 [70334]
   Other proteins in same PDB: d1gq2a2, d1gq2b2, d1gq2c2, d1gq2d2, d1gq2e2, d1gq2f2, d1gq2g2, d1gq2h2, d1gq2i2, d1gq2j2, d1gq2k2, d1gq2l2, d1gq2m2, d1gq2n2, d1gq2o2, d1gq2p2

Details for d1gq2n1

PDB Entry: 1gq2, 2.5 Å

PDB Description: malic enzyme from pigeon liver

SCOP Domain Sequences for d1gq2n1:

Sequence; same for both SEQRES and ATOM records:

>d1gq2n1 c.2.1.7 (N:280-580) Mitochondrial NAD(P)-dependent malic enzyme {Domestic pigeon (Columba livia)}
iqgtasvavagllaalritknrlsdhtvlfqgageaalgianlivmamqkegvskeeaik
riwmvdskglivkgrasltpekehfahehcemknledivkdikptvligvaaiggaftqq
ilqdmaafnkrpiifalsnptskaectaeqlykytegrgifasgspfdpvtlpsgqtlyp
gqgnnsyvfpgvalgviscglkhigddvflttaeviaqevseenlqegrlypplvtiqqv
slkiavriakeayrnntastypqpedleafirsqvystdyncfvadsytwpeeamkvk

Timeline for d1gq2n1:

• d1gq2n1 first appeared in SCOP 1.61
  
• d1gq2n1 appears in SCOP 1.65
  
• d1gq2n1 appears in SCOP 1.69
  
• d1gq2n1 appears in the current release, SCOPe 2.08