SCOP 1.63: Domain d1gpza1: 1gpz A:434-685

Lineage for d1gpza1 (1gpz A:434-685)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (40 proteins)

6. Protein Complement C1R protease, catalytic domain [74976] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [74977] (1 PDB entry)

8. Domain d1gpza1: 1gpz A:434-685 [70302]
   Other proteins in same PDB: d1gpza2, d1gpza3, d1gpzb2, d1gpzb3

Details for d1gpza1

PDB Entry: 1gpz, 2.9 Å

PDB Description: the crystal structure of the zymogen catalytic domain of complement protease c1r

SCOP Domain Sequences for d1gpza1:

Sequence, based on SEQRES records:

>d1gpza1 b.47.1.2 (A:434-685) Complement C1R protease, catalytic domain {Human (Homo sapiens)}
cgkpvnpveqrqqiiggqkakmgnfpwqvftnihgrgggallgdrwiltaahtlypkehe
aqsnasldvflghtnveelmklgnhpirrvsvhpdyrqdesynfegdiallelensvtlg
pnllpiclpdndtfydlglmgyvsgfgvmeekiahdlrfvrlpvanpqacenwlrgknrm
dvfsqnmfcaghpslkqdacqgdsggvfavrdpntdrwvatgivswgigcsrgygfytkv
lnyvdwikkeme

Sequence, based on observed residues (ATOM records):

>d1gpza1 b.47.1.2 (A:434-685) Complement C1R protease, catalytic domain {Human (Homo sapiens)}
cgkpvnpveqrqqiiggqkakmgnfpwqvftnihgrgggallgdrwiltaahtlypkeha
sldvflghtnveelmklgnhpirrvsvhpdyrqdesynfegdiallelensvtlgpnllp
iclpdndtfydlglmgyvsgfgiahdlrfvrlpvanpqacensqnmfcaghpslkqdacq
gdsggvfavrdpntdrwvatgivswgigcsrgygfytkvlnyvdwikkeme

Timeline for d1gpza1:

• d1gpza1 first appeared in SCOP 1.61
  
• d1gpza1 appears in SCOP 1.65
  
• d1gpza1 appears in the current release, SCOPe 2.08