SCOP 1.73: Domain d1ec3b_: 1ec3 B:

Lineage for d1ec3b_ (1ec3 B:)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (230 PDB entries)

8. Domain d1ec3b_: 1ec3 B: [70127]
   complexed with ms3

Details for d1ec3b_

PDB Entry: 1ec3, 1.8 Å

PDB Description: hiv-1 protease in complex with the inhibitor msa367

PDB Compounds: (B:) hiv-1 protease

SCOP Domain Sequences for d1ec3b_:

Sequence; same for both SEQRES and ATOM records:

>d1ec3b_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d1ec3b_:

• d1ec3b_ first appeared in SCOP 1.61
  
• d1ec3b_ appears in SCOP 1.71
  
• d1ec3b_ appears in SCOP 1.75
  
• d1ec3b_ appears in the current release, SCOPe 2.08