SCOPe 2.05: Domain d1d4ia_: 1d4i A:

Lineage for d1d4ia_ (1d4i A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (8 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (446 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d1d4ia_: 1d4i A: [70076]
   complexed with beg

Details for d1d4ia_

PDB Entry: 1d4i, 1.81 Å

PDB Description: HIV-1 protease in complex with the inhibitor BEA425

PDB Compounds: (A:) hiv-1 protease

SCOPe Domain Sequences for d1d4ia_:

Sequence; same for both SEQRES and ATOM records:

>d1d4ia_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d1d4ia_:

• d1d4ia_ first appeared in SCOP 1.61
  
• d1d4ia_ appears in SCOPe 2.04
  
• d1d4ia_ appears in SCOPe 2.06
  
• d1d4ia_ appears in the current release, SCOPe 2.08