Lineage for Protein: Glycogen synthase kinase-3 beta (Gsk3b)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2543788Protein Glycogen synthase kinase-3 beta (Gsk3b) [69823] (2 species)
    CMGC group; GSK3 subfamily; serine/threonine kinase

Species:

  1. 2543789Human (Homo sapiens) [TaxId:9606] [69824] (47 PDB entries)
    Uniprot P49841 35-383 ! Uniprot P49841 35-384
    1. Domains for 1gng:
      1. 2543817Domain d1gnga_: 1gng A: [76239]
        complexed with so4, trs
      2. 2543818Domain d1gngb_: 1gng B: [76240]
        complexed with so4, trs
    2. Domains for 1h8f:
      1. 2543835Domain d1h8fa_: 1h8f A: [65733]
        complexed with epe
      2. 2543836Domain d1h8fb_: 1h8f B: [65734]
        complexed with epe
    3. Domains for 1i09:
      1. 2543845Domain d1i09a_: 1i09 A: [65976]
        complexed with po4
      2. 2543846Domain d1i09b_: 1i09 B: [65977]
        complexed with po4
    4. Domains for 1j1b:
      1. 2543790Domain d1j1ba_: 1j1b A: [90758]
        complexed with anp
      2. 2543791Domain d1j1bb_: 1j1b B: [90759]
        complexed with anp
    5. Domains for 1j1c:
      1. 2543798Domain d1j1ca_: 1j1c A: [90760]
        complexed with adp, mg
      2. 2543799Domain d1j1cb_: 1j1c B: [90761]
        complexed with adp, mg
    6. Domain for 1o9u:
      • 2543814Domain d1o9ua_: 1o9u A: [92691]
        complexed with axin peptide
        complexed with adz
    7. Domains for 1pyx:
      1. 2543810Domain d1pyxa_: 1pyx A: [95383]
        complexed with anp, mg
      2. 2543811Domain d1pyxb_: 1pyx B: [95384]
        complexed with anp, mg
    8. Domains for 1q3d:
      1. 2543800Domain d1q3da_: 1q3d A: [95667]
        complexed with stu
      2. 2543801Domain d1q3db_: 1q3d B: [95668]
        complexed with stu
    9. Domains for 1q3w:
      1. 2543812Domain d1q3wa_: 1q3w A: [95768]
        complexed with atu
      2. 2543813Domain d1q3wb_: 1q3w B: [95769]
        complexed with atu
    10. Domains for 1q41:
      1. 2543794Domain d1q41a_: 1q41 A: [95774]
        complexed with ixm
      2. 2543795Domain d1q41b_: 1q41 B: [95775]
        complexed with ixm
    11. Domains for 1q4l:
      1. 2543822Domain d1q4la_: 1q4l A: [95803]
        complexed with 679
      2. 2543823Domain d1q4lb_: 1q4l B: [95804]
        complexed with 679
    12. Domains for 1q5k:
      1. 2543792Domain d1q5ka_: 1q5k A: [104537]
        complexed with tmu
      2. 2543793Domain d1q5kb_: 1q5k B: [104538]
        complexed with tmu
    13. Domains for 1r0e:
      1. 2543806Domain d1r0ea_: 1r0e A: [111663]
        complexed with dfn, flc
      2. 2543807Domain d1r0eb_: 1r0e B: [111664]
        complexed with dfn, flc
    14. Domain for 1uv5:
    15. Domains for 2jld:
      1. 2543796Domain d2jlda_: 2jld A: [205109]
        automated match to d1j1ba_
        complexed with ag1
      2. 2543797Domain d2jldb_: 2jld B: [205110]
        automated match to d1j1ba_
        complexed with ag1
    16. Domain for 2o5k:
    17. Domains for 2ow3:
      1. 2543863Domain d2ow3a_: 2ow3 A: [149037]
        automated match to d1h8fa_
        complexed with bim
      2. 2543864Domain d2ow3b_: 2ow3 B: [149038]
        automated match to d1h8fa_
        complexed with bim
    18. Domains for 3du8:
      1. 2543824Domain d3du8a_: 3du8 A: [209307]
        automated match to d1pyxa_
        complexed with 553
      2. 2543825Domain d3du8b_: 3du8 B: [209308]
        automated match to d1pyxa_
        complexed with 553
    19. Domains for 3f7z:
      1. 2543847Domain d3f7za1: 3f7z A:35-383 [175555]
        Other proteins in same PDB: d3f7za2, d3f7zb2
        automated match to d1gngb_
        complexed with 34o
      2. 2543848Domain d3f7zb1: 3f7z B:35-383 [175556]
        Other proteins in same PDB: d3f7za2, d3f7zb2
        automated match to d1gngb_
        complexed with 34o
    20. Domains for 3f88:
      1. 2543859Domain d3f88a_: 3f88 A: [175562]
        automated match to d1gngb_
        complexed with 2ht, 3ht
      2. 2543860Domain d3f88b_: 3f88 B: [175563]
        automated match to d1gngb_
        complexed with 2ht, 3ht
    21. Domains for 3i4b:
      1. 2543839Domain d3i4ba_: 3i4b A: [211468]
        automated match to d1q5ka_
        complexed with z48
      2. 2543840Domain d3i4bb_: 3i4b B: [211469]
        automated match to d1q5ka_
        complexed with z48
    22. Domains for 3l1s:
      1. 2543865Domain d3l1sa_: 3l1s A: [232755]
        automated match to d3i4ba_
        complexed with po4, z92
      2. 2543866Domain d3l1sb_: 3l1s B: [232754]
        automated match to d1q5ka_
        complexed with po4, z92
    23. Domains for 3m1s:
      1. 2543833Domain d3m1sa_: 3m1s A: [247577]
        automated match to d1j1bb_
        complexed with dw1
      2. 2543834Domain d3m1sb_: 3m1s B: [247578]
        automated match to d1j1bb_
        complexed with dw1
    24. Domains for 3pup:
      1. 2543837Domain d3pupa_: 3pup A: [214950]
        automated match to d1j1ba_
        complexed with os1
      2. 2543838Domain d3pupb_: 3pup B: [214951]
        automated match to d1j1ba_
        complexed with os1
    25. Domains for 3q3b:
      1. 2543828Domain d3q3ba_: 3q3b A: [215051]
        automated match to d1q41a_
        complexed with 55e
      2. 2543829Domain d3q3bb_: 3q3b B: [215052]
        automated match to d1q41a_
        complexed with 55e
    26. Domains for 3say:
      1. 2543831Domain d3saya_: 3say A: [249327]
        automated match to d1j1bb_
        complexed with fmt, mla, mpd, oft
      2. 2543832Domain d3sayb_: 3say B: [249328]
        automated match to d1j1bb_
        complexed with fmt, mla, mpd, oft
    27. Domains for 3sd0:
      1. 2543819Domain d3sd0a_: 3sd0 A: [200612]
        automated match to d3sd0b_
        complexed with epe, tsk; mutant
      2. 2543820Domain d3sd0b_: 3sd0 B: [196271]
        automated match to d1gngb_
        complexed with epe, tsk; mutant
    28. Domains for 3zrk:
      1. 2543802Domain d3zrka_: 3zrk A: [186533]
        automated match to d1j1bb_
        complexed with gol, so4, zrk
      2. 2543803Domain d3zrkb_: 3zrk B: [186534]
        automated match to d1j1bb_
        complexed with gol, so4, zrk
    29. Domains for 3zrl:
      1. 2543804Domain d3zrla_: 3zrl A: [186535]
        automated match to d1j1bb_
        complexed with gol, so4, zrl
      2. 2543805Domain d3zrlb_: 3zrl B: [186536]
        automated match to d1j1bb_
        complexed with gol, so4, zrl
    30. Domains for 3zrm:
      1. 2543808Domain d3zrma_: 3zrm A: [186537]
        automated match to d1j1bb_
        complexed with gol, so4, zrm
      2. 2543809Domain d3zrmb_: 3zrm B: [186538]
        automated match to d1j1bb_
        complexed with gol, so4, zrm
    31. Domain for 4dit:
    32. Domains for 4iq6:
      1. 2543871Domain d4iq6a_: 4iq6 A: [252670]
        automated match to d1j1bb_
        complexed with iq6
      2. 2543872Domain d4iq6b_: 4iq6 B: [252671]
        automated match to d1j1bb_
        complexed with iq6
    33. Domains for 4j1r:
      1. 2543855Domain d4j1ra_: 4j1r A: [252802]
        automated match to d1j1bb_
        complexed with i5r, k, po4
      2. 2543856Domain d4j1rb_: 4j1r B: [252803]
        automated match to d1j1bb_
        complexed with i5r, k, po4
      3. 2543857Domain d4j1rc_: 4j1r C: [252804]
        automated match to d1j1bb_
        complexed with i5r, k, po4
      4. 2543858Domain d4j1rd_: 4j1r D: [252805]
        automated match to d1j1bb_
        complexed with i5r, k, po4
    34. Domains for 4j71:
      1. 2543841Domain d4j71a_: 4j71 A: [252833]
        automated match to d1j1bb_
        complexed with 1jx, cl, so4
      2. 2543842Domain d4j71b_: 4j71 B: [252834]
        automated match to d1j1bb_
        complexed with 1jx, cl, so4
    35. Domain for 4nm0:
    36. Domains for 4ptc:
      1. 2543861Domain d4ptca_: 4ptc A: [271216]
        automated match to d1j1bb_
        complexed with 2we
      2. 2543862Domain d4ptcb_: 4ptc B: [271215]
        automated match to d1j1bb_
        complexed with 2we
    37. Domains for 4pte:
      1. 2543815Domain d4ptea_: 4pte A: [271207]
        automated match to d1j1bb_
        complexed with 2wf
      2. 2543816Domain d4pteb_: 4pte B: [271208]
        automated match to d1j1bb_
        complexed with 2wf
    38. Domains for 4ptg:
      1. 2543843Domain d4ptga_: 4ptg A: [271206]
        automated match to d1j1bb_
        complexed with 2wg
      2. 2543844Domain d4ptgb_: 4ptg B: [271213]
        automated match to d1j1bb_
        complexed with 2wg
    39. Domains for 5f94:
      1. 2543851Domain d5f94a_: 5f94 A: [314291]
        automated match to d3zrla_
        complexed with 3uo
      2. 2543852Domain d5f94b_: 5f94 B: [314076]
        automated match to d3zrla_
        complexed with 3uo
    40. Domains for 5f95:
      1. 2543853Domain d5f95a_: 5f95 A: [314138]
        automated match to d3zrla_
        complexed with 3up
      2. 2543854Domain d5f95b_: 5f95 B: [314555]
        automated match to d3zrla_
        complexed with 3up
    41. Domains for 5hln:
      1. 2543869Domain d5hlna_: 5hln A: [317782]
        automated match to d1j1bb_
        complexed with 65c, mes, mg
      2. 2543870Domain d5hlnb_: 5hln B: [317787]
        automated match to d1j1bb_
        complexed with 65c, mes, mg
    42. Domains for 5hlp:
      1. 2543849Domain d5hlpa_: 5hlp A: [317763]
        automated match to d1j1bb_
        complexed with 65a
      2. 2543850Domain d5hlpb_: 5hlp B: [317788]
        automated match to d1j1bb_
        complexed with 65a
    43. Domains for 5k5n:
      1. 2543826Domain d5k5na_: 5k5n A: [323024]
        automated match to d1gngb_
        complexed with 6qh, so4
      2. 2543827Domain d5k5nb_: 5k5n B: [323049]
        automated match to d1gngb_
        complexed with 6qh, so4
    44. Domains for 5kpk:
      1. 3046518Domain d5kpka_: 5kpk A: [346580]
        automated match to d1j1bb_
        complexed with 6vk
      2. 3046556Domain d5kpkb_: 5kpk B: [346618]
        automated match to d1j1bb_
        complexed with 6vk
    45. Domains for 5kpl:
      1. 3046457Domain d5kplb_: 5kpl B: [346519]
        automated match to d1j1bb_
        complexed with 6vl
      2. 3046468Domain d5kpla_: 5kpl A: [346530]
        automated match to d1j1bb_
        complexed with 6vl
    46. Domains for 5kpm:
      1. 3046459Domain d5kpmb_: 5kpm B: [346521]
        automated match to d1j1bb_
        complexed with 6vm
      2. 3046566Domain d5kpma_: 5kpm A: [346628]
        automated match to d1j1bb_
        complexed with 6vm
    47. Domains for 6gn1:
      1. 3053632Domain d6gn1a_: 6gn1 A: [353694]
        automated match to d1j1bb_
        complexed with cl, f4n
      2. 3053651Domain d6gn1b_: 6gn1 B: [353713]
        automated match to d1j1bb_
        complexed with cl, f4n
  2. 3057588Mus musculus [TaxId:10090] [357651] (1 PDB entry)

More info for Protein Glycogen synthase kinase-3 beta (Gsk3b) from d.144.1.7: Protein kinases, catalytic subunit

Timeline for Protein Glycogen synthase kinase-3 beta (Gsk3b) from d.144.1.7: Protein kinases, catalytic subunit: