SCOPe 2.05: Protein: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF

Lineage for Protein: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF

Root: SCOPe 2.05
Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
Fold d.79: Bacillus chorismate mutase-like [55297] (9 superfamilies)
core: beta-alpha-beta-alpha-beta(2); mixed beta-sheet: order: 1423, strand 4 is antiparallel to the rest

Superfamily d.79.5: IpsF-like [69765] (2 families)

forms trimers with three closely packed beta-sheets; possible link between the YjgF-like (d.79.1) and 4'-phosphopantetheinyl transferase superfamilies (d.150.1)

Family d.79.5.1: IpsF-like [69766] (3 proteins)
automatically mapped to Pfam PF02542
Protein 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF [69767] (6 species)

Species:

Escherichia coli K-12 [TaxId:83333] [188969] (5 PDB entries)
1. Domains for 3elc:
  1. Domain d3elca_: 3elc A: [175052]
    automated match to d1h48c_
    complexed with f01, gpp, zn
  2. Domain d3elcb_: 3elc B: [175053]
    automated match to d1h48c_
    complexed with f01, gpp, zn
  3. Domain d3elcc_: 3elc C: [175054]
    automated match to d1h48c_
    complexed with f01, gpp, zn
2. Domain for 3eor:
  - Domain d3eora_: 3eor A: [175139]
    automated match to d1h48c_
    complexed with cfv, gpp, na, zn
3. Domains for 3ern:
  1. Domain d3erna_: 3ern A: [175168]
    automated match to d1h48c_
    complexed with car, gpp, so4, zn
  2. Domain d3ernb_: 3ern B: [175169]
    automated match to d1h48c_
    complexed with car, gpp, so4, zn
  3. Domain d3ernc_: 3ern C: [175170]
    automated match to d1h48c_
    complexed with car, gpp, so4, zn
  4. Domain d3ernd_: 3ern D: [175171]
    automated match to d1h48c_
    complexed with car, gpp, so4, zn
  5. Domain d3erne_: 3ern E: [175172]
    automated match to d1h48c_
    complexed with car, gpp, so4, zn
  6. Domain d3ernf_: 3ern F: [175173]
    automated match to d1h48c_
    complexed with car, gpp, so4, zn
4. Domain for 3esj:
  - Domain d3esja_: 3esj A: [175193]
    automated match to d1h48c_
    complexed with cc7, gpp, mg, zn
5. Domain for 3fba:
  - Domain d3fbaa_: 3fba A: [246075]
    automated match to d3esja_
    complexed with c6b, gol, gpp, zn
Escherichia coli [TaxId:562] [69768] (13 PDB entries)
Uniprot P62617 ! Uniprot P36663
1. Domains for 1gx1:
  1. Domain d1gx1a_: 1gx1 A: [70675]
    complexed with cdp, mn, so4, zn
  2. Domain d1gx1b_: 1gx1 B: [70676]
    complexed with cdp, mn, so4, zn
  3. Domain d1gx1c_: 1gx1 C: [70677]
    complexed with cdp, mn, so4, zn
2. Domains for 1h47:
  1. Domain d1h47a_: 1h47 A: [111615]
    complexed with c5p, gpp, zn
  2. Domain d1h47b_: 1h47 B: [111616]
    complexed with c5p, gpp, zn
  3. Domain d1h47c_: 1h47 C: [111617]
    complexed with c5p, gpp, zn
  4. Domain d1h47d_: 1h47 D: [111618]
    complexed with c5p, gpp, zn
  5. Domain d1h47e_: 1h47 E: [111619]
    complexed with c5p, gpp, zn
  6. Domain d1h47f_: 1h47 F: [111620]
    complexed with c5p, gpp, zn
3. Domains for 1h48:
  1. Domain d1h48a_: 1h48 A: [111621]
    complexed with c5p, cdi, gpp, mn, zn
  2. Domain d1h48b_: 1h48 B: [111622]
    complexed with c5p, cdi, gpp, mn, zn
  3. Domain d1h48c_: 1h48 C: [111623]
    complexed with c5p, cdi, gpp, mn, zn
  4. Domain d1h48d_: 1h48 D: [111624]
    complexed with c5p, cdi, gpp, mn, zn
  5. Domain d1h48e_: 1h48 E: [111625]
    complexed with c5p, cdi, gpp, mn, zn
  6. Domain d1h48f_: 1h48 F: [111626]
    complexed with c5p, cdi, gpp, mn, zn
4. Domain for 1jy8:
  - Domain d1jy8a_: 1jy8 A: [67452]
    complexed with c5p, cdi, zn
5. Domain for 1knj:
  - Domain d1knja_: 1knj A: [72778]
    complexed with c5p, cdi, mn
6. Domain for 1knk:
  - Domain d1knka_: 1knk A: [72779]
    complexed with mn
7. Domain for 1u3l:
  - Domain d1u3la_: 1u3l A: [107643]
    complexed with cdp, mg, zn
8. Domain for 1u3p:
  - Domain d1u3pa_: 1u3p A: [107644]
    complexed with zn
9. Domain for 1u40:
  - Domain d1u40a_: 1u40 A: [107647]
    complexed with cdm, zn
10. Domain for 1u43:
  - Domain d1u43a_: 1u43 A: [107653]
    complexed with sud
11. Domain for 1yqn:
  - Domain d1yqna_: 1yqn A: [241057]
    automated match to d3esja_
    complexed with cdp, gpp, mn, zn; mutant
12. Domains for 2amt:
  1. Domain d2amta_: 2amt A: [162834]
    automated match to d1h48c_
    complexed with 1aa, gpp, zn
  2. Domain d2amtb_: 2amt B: [162835]
    automated match to d1h48c_
    complexed with 1aa, gpp, zn
  3. Domain d2amtc_: 2amt C: [162836]
    automated match to d1h48c_
    complexed with 1aa, gpp, zn
  4. Domain d2amtd_: 2amt D: [162837]
    automated match to d1h48c_
    complexed with 1aa, gpp, zn
  5. Domain d2amte_: 2amt E: [162838]
    automated match to d1h48c_
    complexed with 1aa, gpp, zn
  6. Domain d2amtf_: 2amt F: [162839]
    automated match to d1h48c_
    complexed with 1aa, gpp, zn
13. Domain for 2gzl:
  - Domain d2gzla_: 2gzl A: [135909]
    automated match to d1h48c_
    complexed with 2aa, gpp, zn
Haemophilus influenzae [TaxId:727] [75479] (3 PDB entries)
1. Domains for 1jn1:
  1. Domain d1jn1a_: 1jn1 A: [71754]
    structural genomics
    complexed with co, so4
  2. Domain d1jn1b_: 1jn1 B: [71755]
    structural genomics
    complexed with co, so4
  3. Domain d1jn1c_: 1jn1 C: [71756]
    structural genomics
    complexed with co, so4
2. Domains for 1vh8:
  1. Domain d1vh8a_: 1vh8 A: [100647]
    structural genomics
    complexed with acy, pop
  2. Domain d1vh8b_: 1vh8 B: [100648]
    structural genomics
    complexed with acy, pop
  3. Domain d1vh8c_: 1vh8 C: [100649]
    structural genomics
    complexed with acy, pop
  4. Domain d1vh8d_: 1vh8 D: [100650]
    structural genomics
    complexed with acy, pop
  5. Domain d1vh8e_: 1vh8 E: [100651]
    structural genomics
    complexed with acy, pop
  6. Domain d1vh8f_: 1vh8 F: [100652]
    structural genomics
    complexed with acy, pop
3. Domains for 1vha:
  1. Domain d1vhaa_: 1vha A: [100655]
    structural genomics
    complexed with acy, mn, pop
  2. Domain d1vhab_: 1vha B: [100656]
    structural genomics
    complexed with acy, mn, pop
  3. Domain d1vhac_: 1vha C: [100657]
    structural genomics
    complexed with acy, mn, pop
  4. Domain d1vhad_: 1vha D: [100658]
    structural genomics
    complexed with acy, mn, pop
  5. Domain d1vhae_: 1vha E: [100659]
    structural genomics
    complexed with acy, mn, pop
  6. Domain d1vhaf_: 1vha F: [100660]
    structural genomics
    complexed with acy, mn, pop
Shewanella oneidensis [TaxId:70863] [118026] (1 PDB entry)
Uniprot Q8EBR3
- Domains for 1t0a:
  1. Domain d1t0aa_: 1t0a A: [112192]
    complexed with co, fpp, zn
  2. Domain d1t0ab_: 1t0a B: [112193]
    complexed with co, fpp, zn
  3. Domain d1t0ac_: 1t0a C: [112194]
    complexed with co, fpp, zn
Thale cress (Arabidopsis thaliana) [TaxId:3702] [187992] (1 PDB entry)
- Domain for 2pmp:
  - Domain d2pmpa_: 2pmp A: [167219]
    automated match to d1vh8a_
    complexed with c5p, cl, po4, zn
Thermus thermophilus [TaxId:274] [82720] (4 PDB entries)
1. Domains for 1iv1:
  1. Domain d1iv1a_: 1iv1 A: [76816]
  2. Domain d1iv1b_: 1iv1 B: [76817]
  3. Domain d1iv1c_: 1iv1 C: [76818]
  4. Domain d1iv1d_: 1iv1 D: [76819]
  5. Domain d1iv1e_: 1iv1 E: [76820]
  6. Domain d1iv1f_: 1iv1 F: [76821]
2. Domains for 1iv2:
  1. Domain d1iv2a_: 1iv2 A: [76822]
    complexed with cdp, mg
  2. Domain d1iv2b_: 1iv2 B: [76823]
    complexed with cdp, mg
  3. Domain d1iv2c_: 1iv2 C: [76824]
    complexed with cdp, mg
  4. Domain d1iv2d_: 1iv2 D: [76825]
    complexed with cdp, mg
  5. Domain d1iv2e_: 1iv2 E: [76826]
    complexed with cdp, mg
  6. Domain d1iv2f_: 1iv2 F: [76827]
    complexed with cdp, mg
3. Domains for 1iv3:
  1. Domain d1iv3a_: 1iv3 A: [76828]
    complexed with mg
  2. Domain d1iv3b_: 1iv3 B: [76829]
    complexed with mg
  3. Domain d1iv3c_: 1iv3 C: [76830]
    complexed with mg
  4. Domain d1iv3d_: 1iv3 D: [76831]
    complexed with mg
  5. Domain d1iv3e_: 1iv3 E: [76832]
    complexed with mg
  6. Domain d1iv3f_: 1iv3 F: [76833]
    complexed with mg
4. Domains for 1iv4:
  1. Domain d1iv4a_: 1iv4 A: [76834]
    complexed with c5p, mg
  2. Domain d1iv4b_: 1iv4 B: [76835]
    complexed with c5p, mg
  3. Domain d1iv4c_: 1iv4 C: [76836]
    complexed with c5p, mg
  4. Domain d1iv4d_: 1iv4 D: [76837]
    complexed with c5p, mg
  5. Domain d1iv4e_: 1iv4 E: [76838]
    complexed with c5p, mg
  6. Domain d1iv4f_: 1iv4 F: [76839]
    complexed with c5p, mg

More info for Protein 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from d.79.5.1: IpsF-like

Timeline for Protein 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from d.79.5.1: IpsF-like:

Protein 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from d.79.5.1: IpsF-like first appeared in SCOP 1.59, called Protein 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from d.79.5.1: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF
Protein 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from d.79.5.1: IpsF-like appears in SCOPe 2.04
Protein 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from d.79.5.1: IpsF-like appears in SCOPe 2.06
Protein 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from d.79.5.1: IpsF-like appears in the current release, SCOPe 2.08