SCOPe 2.06: Family c.113.1.1: HemD-like

Lineage for Family c.113.1.1: HemD-like

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.113: HemD-like [69617] (1 superfamily)
   duplication: consists of two similar 'swapped' domain with 3 layers (a/b/a) each; parallel beta-sheet of 5 strands, order 21345

4. Superfamily c.113.1: HemD-like [69618] (1 family)
   automatically mapped to Pfam PF02602

5. Family c.113.1.1: HemD-like [69619] (3 proteins)
   Pfam PF02602

Proteins:

1. Probable uroporphyrinogen-III synthase [117738] (1 species)

   • Species Thermus thermophilus [TaxId:274] [117739] (1 PDB entry)
     Uniprot Q5SKH2; TTHA0671

2. Uroporphyrinogen III synthase (U3S, HemD) [69620] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69621] (1 PDB entry)

3. automated matches [190804] (2 species)
   not a true protein

   1. Species Thermus thermophilus [TaxId:262724] [255795] (4 PDB entries)

   2. Species Thermus thermophilus [TaxId:274] [188071] (2 PDB entries)

More info for Family c.113.1.1: HemD-like

Timeline for Family c.113.1.1: HemD-like:

• Family c.113.1.1: HemD-like first appeared in SCOP 1.59, called Family c.113.1.1: Uroporphyrinogen III synthase (U3S, HemD)
  
• Family c.113.1.1: HemD-like appears in SCOPe 2.05
  
• Family c.113.1.1: HemD-like appears in SCOPe 2.07
  
• Family c.113.1.1: HemD-like appears in the current release, SCOPe 2.08