SCOPe 2.08: Domain d1kfxl1: 1kfx L:515-700

Lineage for d1kfxl1 (1kfx L:515-700)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (12 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.8: Penta-EF-hand proteins [63550] (7 proteins)

6. Protein Calpain large subunit, C-terminal domain (domain IV) [47556] (3 species)

7. Species Human (Homo sapiens), M-type [TaxId:9606] [47557] (2 PDB entries)

8. Domain d1kfxl1: 1kfx L:515-700 [68575]
   Other proteins in same PDB: d1kfxl2, d1kfxl3, d1kfxs_

Details for d1kfxl1

PDB Entry: 1kfx, 3.15 Å

PDB Description: Crystal Structure of Human m-Calpain Form I

PDB Compounds: (L:) m-calpain large subunit

SCOPe Domain Sequences for d1kfxl1:

Sequence, based on SEQRES records:

>d1kfxl1 a.39.1.8 (L:515-700) Calpain large subunit, C-terminal domain (domain IV) {Human (Homo sapiens), M-type [TaxId: 9606]}
eieanleefdiseddiddgvrrlfaqlagedaeisafelqtilrrvlakrqdiksdgfsi
etckimvdmldsdgsgklglkefyilwtkiqkyqkiyreidvdrsgtmnsyemrkaleea
gfkmpcqlhqvivarfaddqliidfdnfvrclvrletlfkifkqldpentgtieldlisw
lcfsvl

Sequence, based on observed residues (ATOM records):

>d1kfxl1 a.39.1.8 (L:515-700) Calpain large subunit, C-terminal domain (domain IV) {Human (Homo sapiens), M-type [TaxId: 9606]}
eieanleefdiseddiddgvrrlfaqlagedaeisafelqtilrrvlakrksdgfsietc
kimvdmldsdgsgklglkefyilwtkiqkyqkiyreidvdrsgtmnsyemrkaleeagfk
mpcqlhqvivarfaddqliidfdnfvrclvrletlfkifkqldpentgtieldliswlcf
svl

Timeline for d1kfxl1:

• d1kfxl1 first appeared in SCOP 1.59
  
• d1kfxl1 appears in SCOPe 2.07