SCOPe 2.06: Domain d1jy1a2: 1jy1 A:351-608

Lineage for d1jy1a2 (1jy1 A:351-608)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.136: Phospholipase D/nuclease [56023] (1 superfamily)
   beta-alpha-beta-alpha-beta-alpha-beta(4)-alpha; mixed sheet: order 1765234

4. Superfamily d.136.1: Phospholipase D/nuclease [56024] (6 families)

5. Family d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 [69815] (2 proteins)

6. Protein Tyrosyl-DNA phosphodiesterase TDP1 [69816] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69817] (12 PDB entries)

8. Domain d1jy1a2: 1jy1 A:351-608 [67439]
   Other proteins in same PDB: d1jy1a3

Details for d1jy1a2

PDB Entry: 1jy1, 1.69 Å

PDB Description: crystal structure of human tyrosyl-dna phosphodiesterase (tdp1)

PDB Compounds: (A:) tyrosyl-DNA phosphodiesterase

SCOPe Domain Sequences for d1jy1a2:

Sequence, based on SEQRES records:

>d1jy1a2 d.136.1.3 (A:351-608) Tyrosyl-DNA phosphodiesterase TDP1 {Human (Homo sapiens) [TaxId: 9606]}
nvyligstpgrfqgsqkdnwghfrlkkllkdhassmpnaeswpvvgqfssvgslgadesk
wlcsefkesmltlgkesktpgkssvplyliypsvenvrtslegypaggslpysiqtaekq
nwlhsyfhkwsaetsgrsnamphiktymrpspdfskiawflvtsanlskaawgalekngt
qlmirsyelgvlflpsalgldsfkvkqkffagsqepmatfpvpydlppelygskdrpwiw
nipyvkapdthgnmwvps

Sequence, based on observed residues (ATOM records):

>d1jy1a2 d.136.1.3 (A:351-608) Tyrosyl-DNA phosphodiesterase TDP1 {Human (Homo sapiens) [TaxId: 9606]}
nvyligstpgrfqgsqkdnwghfrlkkllkdhaaeswpvvgqfssvgslgadeskwlcse
fkesmltlgsvplyliypsvenvrtslegypaggslpysiqtaekqnwlhsyfhkwsaet
sgrsnamphiktymrpspdfskiawflvtsanlskaawgalekngtqlmirsyelgvlfl
psalgldsfkvkatfpvpydlppelygskdrpwiwnipyvkapdthgnmwvps

Timeline for d1jy1a2:

• d1jy1a2 first appeared in SCOP 1.59
  
• d1jy1a2 appears in SCOPe 2.05
  
• d1jy1a2 appears in SCOPe 2.07
  
• d1jy1a2 appears in the current release, SCOPe 2.08