Lineage for d1jlea2 (1jle A:1-429)

  1. Root: SCOPe 2.02
  2. 1232558Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)
  3. 1234135Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 1234136Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 1234302Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)
  6. 1234303Protein HIV-1 reverse transcriptase [56689] (3 species)
  7. 1234322Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (114 PDB entries)
    Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
  8. 1234481Domain d1jlea2: 1jle A:1-429 [66843]
    Other proteins in same PDB: d1jlea1
    mutant

Details for d1jlea2

PDB Entry: 1jle (more details), 2.8 Å

PDB Description: crystal structure of y188c mutant hiv-1 reverse transcriptase
PDB Compounds: (A:) hiv-1 rt, a-chain

SCOPe Domain Sequences for d1jlea2:

Sequence, based on SEQRES records: (download)

>d1jlea2 e.8.1.2 (A:1-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
yqymddlcvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyql

Sequence, based on observed residues (ATOM records): (download)

>d1jlea2 e.8.1.2 (A:1-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
pispietvpvklkpgmdgpqwplteekikalveictemekegkiskinpyntpvfklvdf
relnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinn
etpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlcvgsdleigq
hrtkieelrqhllrwglttpkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqk
lvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyy
dpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittes
iviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql

SCOPe Domain Coordinates for d1jlea2:

Click to download the PDB-style file with coordinates for d1jlea2.
(The format of our PDB-style files is described here.)

Timeline for d1jlea2:

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Domains from same chain:
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d1jlea1
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Domains from other chains:
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d1jleb_