SCOP 1.75: Domain d1jkha1: 1jkh A:430-554

Lineage for d1jkha1 (1jkh A:430-554)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (14 families)
   consists of one domain of this fold

5. Family c.55.3.1: Ribonuclease H [53099] (4 proteins)

6. Protein HIV RNase H (Domain of reverse transcriptase) [53105] (2 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [53106] (85 PDB entries)
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582
   Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584
   Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595

8. Domain d1jkha1: 1jkh A:430-554 [66797]
   Other proteins in same PDB: d1jkha2, d1jkhb_
   complexed with efz; mutant

Details for d1jkha1

PDB Entry: 1jkh, 2.5 Å

PDB Description: crystal structure of y181c mutant hiv-1 reverse transcriptase in complex with dmp-266(efavirenz)

PDB Compounds: (A:) hiv-1 rt, a-chain

SCOP Domain Sequences for d1jkha1:

Sequence; same for both SEQRES and ATOM records:

>d1jkha1 c.55.3.1 (A:430-554) HIV RNase H (Domain of reverse transcriptase) {Human immunodeficiency virus type 1 [TaxId: 11676]}
ekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelqaiylalqds
glevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahkgiggneqvd
klvsa

Timeline for d1jkha1:

• d1jkha1 first appeared in SCOP 1.59
  
• d1jkha1 appears in SCOP 1.73
  
• d1jkha1 appears in SCOPe 2.01
  
• d1jkha1 appears in the current release, SCOPe 2.08