SCOPe 2.04: Domain d1h7ub2: 1h7u B:32-231

Lineage for d1h7ub2 (1h7u B:32-231)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.2: DNA gyrase/MutL, N-terminal domain [55879] (7 proteins)

6. Protein DNA mismatch repair protein PMS2 [69800] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69801] (3 PDB entries)

8. Domain d1h7ub2: 1h7u B:32-231 [65712]
   Other proteins in same PDB: d1h7ua1, d1h7ub1
   complexed with ags, mg

Details for d1h7ub2

PDB Entry: 1h7u, 2.7 Å

PDB Description: nhpms2-atpgs

PDB Compounds: (B:) mismatch repair endonuclease pms2

SCOPe Domain Sequences for d1h7ub2:

Sequence, based on SEQRES records:

>d1h7ub2 d.122.1.2 (B:32-231) DNA mismatch repair protein PMS2 {Human (Homo sapiens) [TaxId: 9606]}
vlslstavkelvensldagatnidlklkdygvdlievsdngcgveeenfegltlkhhtsk
iqefadltqvetfgfrgealsslcalsdvtistchasakvgtrlmfdhngkiiqktpypr
prgttvsvqqlfstlpvrhkefqrnikkeyakmvqvlhayciisagirvsctnqlgqgkr
qpvvctggspsikenigsvf

Sequence, based on observed residues (ATOM records):

>d1h7ub2 d.122.1.2 (B:32-231) DNA mismatch repair protein PMS2 {Human (Homo sapiens) [TaxId: 9606]}
vlslstavkelvensldagatnidlklkdygvdlievsdngcgveeenfegltlealssl
calsdvtistchasakvgtrlmfdhngkiiqktpyprprgttvsvqqlfstlpvrhkefq
rnikkeyakmvqvlhayciisagirvsctnqlgqgkrqpvvctggspsikenigsvf

Timeline for d1h7ub2:

• d1h7ub2 first appeared in SCOP 1.59
  
• d1h7ub2 appears in SCOPe 2.03
  
• d1h7ub2 appears in SCOPe 2.05
  
• d1h7ub2 appears in the current release, SCOPe 2.08