SCOPe 2.05: Domain d1h7sa2: 1h7s A:29-231

Lineage for d1h7sa2 (1h7s A:29-231)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.2: DNA gyrase/MutL, N-terminal domain [55879] (7 proteins)

6. Protein DNA mismatch repair protein PMS2 [69800] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69801] (3 PDB entries)

8. Domain d1h7sa2: 1h7s A:29-231 [65706]
   Other proteins in same PDB: d1h7sa1, d1h7sb1

Details for d1h7sa2

PDB Entry: 1h7s, 1.95 Å

PDB Description: n-terminal 40kda fragment of human pms2

PDB Compounds: (A:) pms1 protein homolog 2

SCOPe Domain Sequences for d1h7sa2:

Sequence, based on SEQRES records:

>d1h7sa2 d.122.1.2 (A:29-231) DNA mismatch repair protein PMS2 {Human (Homo sapiens) [TaxId: 9606]}
gqvvlslstavkelvensldagatnidlklkdygvdlievsdngcgveeenfegltlkhh
tskiqefadltqvetfgfrgealsslcalsdvtistchasakvgtrlmfdhngkiiqktp
yprprgttvsvqqlfstlpvrhkefqrnikkeyakmvqvlhayciisagirvsctnqlgq
gkrqpvvctggspsikenigsvf

Sequence, based on observed residues (ATOM records):

>d1h7sa2 d.122.1.2 (A:29-231) DNA mismatch repair protein PMS2 {Human (Homo sapiens) [TaxId: 9606]}
gqvvlslstavkelvensldagatnidlklkdygvdlievsdngcgveeenfegltladl
tqvetfgfrgealsslcalsdvtistchasakvgtrlmfdhngkiiqktpyprprgttvs
vqqlfstlpvrhkefqrnikkeyakmvqvlhayciisagirvsctnqlgqgkrqpvvctg
gspsikenigsvf

Timeline for d1h7sa2:

• d1h7sa2 first appeared in SCOP 1.59
  
• d1h7sa2 appears in SCOPe 2.04
  
• d1h7sa2 appears in SCOPe 2.06
  
• d1h7sa2 appears in the current release, SCOPe 2.08