SCOPe 2.01: Domain d1ez4c1: 1ez4 C:16-162

Lineage for d1ez4c1 (1ez4 C:16-162)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.5: LDH N-terminal domain-like [51848] (8 proteins)

6. Protein Lactate dehydrogenase [51859] (14 species)

7. Species Lactobacillus pentosus [TaxId:1589] [69418] (1 PDB entry)

8. Domain d1ez4c1: 1ez4 C:16-162 [64921]
   Other proteins in same PDB: d1ez4a2, d1ez4b2, d1ez4c2, d1ez4d2
   complexed with nad

Details for d1ez4c1

PDB Entry: 1ez4, 2.3 Å

PDB Description: crystal structure of non-allosteric l-lactate dehydrogenase from lactobacillus pentosus at 2.3 angstrom resolution

PDB Compounds: (C:) lactate dehydrogenase

SCOPe Domain Sequences for d1ez4c1:

Sequence, based on SEQRES records:

>d1ez4c1 c.2.1.5 (C:16-162) Lactate dehydrogenase {Lactobacillus pentosus [TaxId: 1589]}
smpnhqkvvlvgdgavgssyafamaqqgiaeefvivdvvkdrtkgdaldledaqaftapk
kiysgeysdckdadlvvitagapqkpgesrldlvnknlnilssivkpvvdsgfdgiflva
anpvdiltyatwkfsgfpkervigsg

Sequence, based on observed residues (ATOM records):

>d1ez4c1 c.2.1.5 (C:16-162) Lactate dehydrogenase {Lactobacillus pentosus [TaxId: 1589]}
smpnhqkvvlvgdgavgssyafamaqqgiaeefvivdvvkdrtkgdaldledaqaftapk
kiysgeysdckdadlvvitagalvnknlnilssivkpvvdsgfdgiflvaanpvdiltya
twkfsgfpkervigsg

Timeline for d1ez4c1:

• d1ez4c1 first appeared in SCOP 1.59
  
• d1ez4c1 appears in SCOP 1.75
  
• d1ez4c1 appears in SCOPe 2.02
  
• d1ez4c1 appears in the current release, SCOPe 2.08