SCOPe 2.06: Family d.144.1.6: APH phosphotransferases

Lineage for Family d.144.1.6: APH phosphotransferases

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.6: APH phosphotransferases [64411] (5 proteins)

Proteins:

1. Aminoglycoside 3'-phosphotransferase IIa (Kanamycin kinase) [103302] (1 species)

   • Species Klebsiella pneumoniae [TaxId:573] [103303] (1 PDB entry)

2. Homoserine kinase ThrB [160816] (1 species)

   • Species Agrobacterium tumefaciens [TaxId:358] [160817] (1 PDB entry)
     Uniprot Q8UHA8 5-320

3. Methylthioribose kinase MtnK [160814] (1 species)

   • Species Bacillus subtilis [TaxId:1423] [160815] (6 PDB entries)
     Uniprot O31663 5-396

4. RdoA [160818] (1 species)
   Hypothetical protein YihE

   • Species Escherichia coli [TaxId:562] [160819] (1 PDB entry)
     Uniprot P0C0K3 4-328

5. Type IIIa 3',5"-aminoglycoside phosphotransferase [64412] (1 species)

   • Species Enterococcus faecalis [TaxId:1351] [64413] (10 PDB entries)

More info for Family d.144.1.6: APH phosphotransferases

Timeline for Family d.144.1.6: APH phosphotransferases:

• Family d.144.1.6: APH phosphotransferases first appeared in SCOP 1.57, called Family d.144.1.6: Type IIIa 3',5"-aminoglycoside phosphotransferase
  
• Family d.144.1.6: APH phosphotransferases appears in SCOPe 2.05
  
• Family d.144.1.6: APH phosphotransferases appears in SCOPe 2.07
  
• Family d.144.1.6: APH phosphotransferases appears in the current release, SCOPe 2.08